<p><b>Bold</b> indicates positions unique to the HCC or cirrhotic sequence alignments compared to alignments of randomly selected HCV control sequences.</p
<p>Numbers shown below the sequence represent the nucleotide position in the HCV complete genome. Th...
<p>Sequences of IRRDR[2a] (interferon/ribavirin resistance-determining region of HCV-2a) obtained fr...
<p>Sequences of ISDR/+C[2a] (part of interferon sensitivity determining-region plus its carboxy-flan...
<p><b>Bold</b> indicates positions unique to HALT-C compared to random control alignments.</p
Amino acid alignment of all our HCV sequences in comparison with the HCV prototype strain H77 indica...
<p>Amino acid covariances within alignments of the HCV cirrhotic (left) and HCC (right) sequences we...
<p>**Sites detected as statistically significant by two methods.</p><p>Statistically significant val...
<p>Positions where the distribution of amino acids differ in HCC and cirrhotic control sequences.</p
<p>Codon variability at HCV NS5A positions associated with major drug resistance to NS5A inhibitors ...
a<p>The wild-type amino-acid of HCV genotype 1b at each position associated with drug resistance is ...
a<p>The wild-type amino-acid of HCV genotype 1b at each position associated with drug resistance is ...
<p>It shows the mean diversity within the sequences detecting each genotype based on comparison of s...
<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...
<p>A, amino acid sequences of multiple UL144 genotype in nine patients. B, amino acid sequences of m...
<p>Sequences of IRRDR/N[2b] (an N-terminal part of interferon/ribavirin resistance-determining regio...
<p>Numbers shown below the sequence represent the nucleotide position in the HCV complete genome. Th...
<p>Sequences of IRRDR[2a] (interferon/ribavirin resistance-determining region of HCV-2a) obtained fr...
<p>Sequences of ISDR/+C[2a] (part of interferon sensitivity determining-region plus its carboxy-flan...
<p><b>Bold</b> indicates positions unique to HALT-C compared to random control alignments.</p
Amino acid alignment of all our HCV sequences in comparison with the HCV prototype strain H77 indica...
<p>Amino acid covariances within alignments of the HCV cirrhotic (left) and HCC (right) sequences we...
<p>**Sites detected as statistically significant by two methods.</p><p>Statistically significant val...
<p>Positions where the distribution of amino acids differ in HCC and cirrhotic control sequences.</p
<p>Codon variability at HCV NS5A positions associated with major drug resistance to NS5A inhibitors ...
a<p>The wild-type amino-acid of HCV genotype 1b at each position associated with drug resistance is ...
a<p>The wild-type amino-acid of HCV genotype 1b at each position associated with drug resistance is ...
<p>It shows the mean diversity within the sequences detecting each genotype based on comparison of s...
<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...
<p>A, amino acid sequences of multiple UL144 genotype in nine patients. B, amino acid sequences of m...
<p>Sequences of IRRDR/N[2b] (an N-terminal part of interferon/ribavirin resistance-determining regio...
<p>Numbers shown below the sequence represent the nucleotide position in the HCV complete genome. Th...
<p>Sequences of IRRDR[2a] (interferon/ribavirin resistance-determining region of HCV-2a) obtained fr...
<p>Sequences of ISDR/+C[2a] (part of interferon sensitivity determining-region plus its carboxy-flan...
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