<p>Sequences of IRRDR/N[2b] (an N-terminal part of interferon/ribavirin resistance-determining region of HCV-2b) obtained from RVR and non-RVR patients are aligned. The consensus sequence (Cons) is shown on the top. The numbers along the sequence indicate the aa positions. Dots indicate residues identical to those of the Cons sequence. The numbers of the mutations in IRRDR/N[2b] and the final treatment outcome of each patient are shown on the right.</p
<p>A, amino acid sequences of multiple UL144 genotype in nine patients. B, amino acid sequences of m...
Combination therapy with interferon (IFN) and ribavirin for 24 to 48 weeks is the current standard t...
Different types of interferon are widely used to treat hepatitis C virus (HCV) infection. Results ob...
<p>Sequences of IRRDR[2a] (interferon/ribavirin resistance-determining region of HCV-2a) obtained fr...
<p>Sequences of ISDR/+C[2a] (part of interferon sensitivity determining-region plus its carboxy-flan...
Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chroni...
Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chroni...
<div><p>Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment fo...
<p>*Mean ± S.D.</p><p>Abbreviations: SVR, sustained virological response; RVR, rapid virological res...
<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...
Patients infected with genotype 2b hepatitis C virus (HCV) generally can achieve favorable responses...
<p>Multiple alignment of NS4B amino acid (aa) 1–70 sequences from representative HCV strains of conf...
<p>Non-synonymous mutations at nucleotides 223 and 317 are boxed; 10 synonymous mutations specific f...
Hepatitis C virus (HCV) is a major cause of liver disease throughout the world. The NS5A and E2 prot...
Background: Amino acid variations in several HCV genomic regions have been reported to be associated...
<p>A, amino acid sequences of multiple UL144 genotype in nine patients. B, amino acid sequences of m...
Combination therapy with interferon (IFN) and ribavirin for 24 to 48 weeks is the current standard t...
Different types of interferon are widely used to treat hepatitis C virus (HCV) infection. Results ob...
<p>Sequences of IRRDR[2a] (interferon/ribavirin resistance-determining region of HCV-2a) obtained fr...
<p>Sequences of ISDR/+C[2a] (part of interferon sensitivity determining-region plus its carboxy-flan...
Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chroni...
Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chroni...
<div><p>Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment fo...
<p>*Mean ± S.D.</p><p>Abbreviations: SVR, sustained virological response; RVR, rapid virological res...
<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...
Patients infected with genotype 2b hepatitis C virus (HCV) generally can achieve favorable responses...
<p>Multiple alignment of NS4B amino acid (aa) 1–70 sequences from representative HCV strains of conf...
<p>Non-synonymous mutations at nucleotides 223 and 317 are boxed; 10 synonymous mutations specific f...
Hepatitis C virus (HCV) is a major cause of liver disease throughout the world. The NS5A and E2 prot...
Background: Amino acid variations in several HCV genomic regions have been reported to be associated...
<p>A, amino acid sequences of multiple UL144 genotype in nine patients. B, amino acid sequences of m...
Combination therapy with interferon (IFN) and ribavirin for 24 to 48 weeks is the current standard t...
Different types of interferon are widely used to treat hepatitis C virus (HCV) infection. Results ob...