Amino acid covariance networks for the HCC and cirrhotic sequences.

<p>Amino acid covariances within alignments of the HCV cirrhotic (left) and HCC (right) sequences were graphed with the covarying positions (nodes) represented as circles and the covariances between the positions (edges) as lines. The size of the nodes is proportional to the number of edges that they contact. Yellow nodes are within structural proteins and green nodes are in non-structural proteins. The amino acid residue position numbered relative to the HCV polyprotein is indicated in the larger nodes.