Parasite burden.

<p>Clinical outcomes following <i>L</i>. <i>donovani</i> challenge in hamsters immunized with rLdSir2RP+BCG. On day 21 after the booster, the hamsters of infected, BCG alone and vaccinated groups were challenged intracardially with 10^<b>7</b> metacyclic promastigotes of <i>L</i>. <i>donovani</i>. Following parameters observed Body weight (a), spleen weight (b), liver weight (c), Parasite burden (no. of amastigotes per 100 cell nuclei) in the spleen(d), liver(e), and bone marrow (f) on days 45 and 60 p.c. Significance values indicate the difference between the vaccinated groups and infected group (***, p<0.001). Data represent mean values standard errors (SE) at the designated time points.