Analysis of proapoptotic and antiapoptotic molecules in B16 melanoma cells after treatment with cytostatic drugs.

<p>Representative Western blot results (A) as well as densitometric analysis of performed Western blots for Bax (B), Bcl-2 (C), cleaved caspase 3 (D) as well as cleaved PARP (E) expression in B16 melanoma cells after treatment with genistein, betulin or fingolimod for 72 h, respectively (mean ± SD, n = 3). The signal strength given by the adjusted volume of the bands of the respective proteins was calculated in comparison to the respective β-actin band of each sample. Significance was determined by an unpaired t-test.