Highly informative genes on a genetic interaction network.

<p><b>(A)</b> Genes are grouped into five separate modules that are distinct from the core network. Ontology of pathways and compositions of transporter complexes are based on EcoCyc for <i>E</i>. <i>coli</i> K-12 MG1655. Green edges represent genetic interactions identified in [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004127#pcbi.1004127.ref047" target="_blank">47</a>]. Histograms show frequencies of MI genes for different classifiers for 5 pathway modules. <b>(B)</b> A higher resolution representation for the biosynthesis and transporter complex pathways that are highly enriched in a number of classifiers. Genes shown are the top-ranked in each classification task. The node color denote the classification task that it is highly informative of (task legend on the upper right of the figure).