Effect of con-G on GluN2A localization patterns.

<p>Distinct GluN2A localization around the soma was disrupted by MCAO in the ipsilateral region (A, D) compared to the contralateral region (arrows) (B, E). Clusters of GluN2A were observed in the peri-infarct region of non-treated stroked rat brains (arrows) (C), but this was not observed in con-G-treated brains at 4 hr (F). At 26 hr post-MCAO, perinuclear staining of GluN2A was observed (arrows) (G, J) in the ipsilateral region compared to GluN2A staining observed in the soma of the contralateral region (arrows) (H, K). The peri-infarct of non-treated stroked rat brains showed no specific GluN2A staining (I), but the con-G-treated rat brains showed increased perinuclear presence of GluN2A (arrow) (L). Magnification, 100X. Bar scale, 100 μm for all images.