GluN1 localization pattern in non-treated and con-G-treated stroked rats at 4 hr and 26 hr.

<p>Random punctate staining of GluN1 (red) observed in the ipsilateral regions of stroked rat brain sections at 4 hr (A, D). In the contralateral regions of non-treated (B, 4 hr; H, 26 hr) and-con-G treated stroked rat brains (E, 4 hr; K, 26 hr), distinct GluN1 staining around the soma (blue) is observed (arrows). At 4 hr, the peri-infarct regions of non-treated brains showed similar random punctate staining of GluN1 (C) as the ipsilateral regions; however, the conG-treated stroked rats showed GluN1 staining around the soma (arrows) (F). At 26 hr, the ipsilateral regions of non-treated and con-G-treated-stroked rat brains showed loss of GluN1 staining around the soma (G, J), compared to the contralateral regions (H, K). At 26 hr, the peri-infarct region of non-treated stroked rat brains showed punctate GluN1 staining in the soma (arrow) (I), but the con-G-treated rat brains showed concentrated clusters of somal GluN1 (arrows) (L). Magnification, 100X. Bar scale, 100 μm for all images.