<p>Column wise, the AWM compares correlations between phenotypes, and row wise AWM compares gene-gene interactions. Cells within the matrix correspond to normalized additive effects of gene-associated SNPs as obtained from genome-wide association studies. Squares of blue and yellow color gradients visualize the strength of standardized additive gene (SNP) effects. Abbreviations of phenotypic traits as defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124574#pone.0124574.t001" target="_blank">Table 1</a>.</p
<p>The intensity of the box shadings is proportional to the strength of the gene-based significant a...
<p>The matrix shows the correlations among the expression levels of 103 genes and the values of 104 ...
<p>The strength of association for known (bottom) and unknown (top) metabolites is indicated as the ...
In this chapter we describe the Association Weight Matrix (AWM), a novel procedure to exploit the re...
<p>For each of the loading plots obtained from the 12 <i>judges</i>, we construct a matrix of correl...
<p>Correlation matrix between the 28 lead SNPs calculated from SNP effects on 32 traits (reordered f...
<p>Association strength 0.8 and threshold for the QTN were used. (A) The correlation coefficient m...
<p>(A) The correlation matrix of 53 asthma-related clinical traits. A pixel at row and column corr...
<p>For each SNP in the genes shown on the x-axis, the-log10 <i>P</i> (unadjusted <i>P</i> value) fro...
<p>All SNPs from single marker analyses with a nominal <i>P</i><10<sup>−5</sup> are shown. Associati...
<p>Results are depicted for T5, T6, and the T5-T6 difference. A nominal <i>P</i> ≤ 10<sup>–5</sup> i...
<p>upper side triangle are phenotypic correlations, lower side triangle are genetic correlations wit...
<p><b>Part A</b> depicts association analyses performed by the PLINK software for each SNP. The X ax...
<p>SNP genotypes from genome-wide Illumina array. In the panel displaying BMI association <i>P</i>-v...
Genetic association results (p values) for pair-wise SNPs interactions (allelic model).</p
<p>The intensity of the box shadings is proportional to the strength of the gene-based significant a...
<p>The matrix shows the correlations among the expression levels of 103 genes and the values of 104 ...
<p>The strength of association for known (bottom) and unknown (top) metabolites is indicated as the ...
In this chapter we describe the Association Weight Matrix (AWM), a novel procedure to exploit the re...
<p>For each of the loading plots obtained from the 12 <i>judges</i>, we construct a matrix of correl...
<p>Correlation matrix between the 28 lead SNPs calculated from SNP effects on 32 traits (reordered f...
<p>Association strength 0.8 and threshold for the QTN were used. (A) The correlation coefficient m...
<p>(A) The correlation matrix of 53 asthma-related clinical traits. A pixel at row and column corr...
<p>For each SNP in the genes shown on the x-axis, the-log10 <i>P</i> (unadjusted <i>P</i> value) fro...
<p>All SNPs from single marker analyses with a nominal <i>P</i><10<sup>−5</sup> are shown. Associati...
<p>Results are depicted for T5, T6, and the T5-T6 difference. A nominal <i>P</i> ≤ 10<sup>–5</sup> i...
<p>upper side triangle are phenotypic correlations, lower side triangle are genetic correlations wit...
<p><b>Part A</b> depicts association analyses performed by the PLINK software for each SNP. The X ax...
<p>SNP genotypes from genome-wide Illumina array. In the panel displaying BMI association <i>P</i>-v...
Genetic association results (p values) for pair-wise SNPs interactions (allelic model).</p
<p>The intensity of the box shadings is proportional to the strength of the gene-based significant a...
<p>The matrix shows the correlations among the expression levels of 103 genes and the values of 104 ...
<p>The strength of association for known (bottom) and unknown (top) metabolites is indicated as the ...