<p>Results are depicted for T5, T6, and the T5-T6 difference. A nominal <i>P</i> ≤ 10<sup>–5</sup> is indicated with a red line for each trait. The triangular heat map depicts the degree of LD, <i>r</i><sup>2</sup>, between variants. The five major chromosome arms are delineated by the black lines. Red corresponds to complete LD and blue to absence of LD. The upper panels show the mixed model significance threshold (-log10(<i>P</i>)) and the effect size in phenotypic standard deviation units (<i>a</i>/<i>σp</i>) for each trait. The minor allele frequency (MAF) is shown on the bottom panel.</p
<p><b>(A)</b> The heatmap above indicates LD distribution. The color density represents the average ...
We estimated the median size of genomic regions with pronounced linkage at F20 by the autocorrelatio...
A major finding from the last decade of genome-wide association studies (GWAS) is that variant-pheno...
<p>All SNPs from single marker analyses with a nominal <i>P</i><10<sup>−5</sup> are shown. Associati...
<p>Manhattan plots and accompanying linkage disequilibrium heat maps are depicted for the (A) <i>e r...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...
<p>the y axis represents–log<sub>10</sub> (p values) and the x axis shows position within <i>MUC5B</...
<p>Panels on the left are regional association plots for all variants in the MHC region; each diamon...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...
<p>(<b>A</b>) Manhattan-plot showing the negative decadic logarithms of the raw P values obtained fr...
<p>The strengths of genome-wide association studies (GWAS) are illustrated by the Manhattan plots on...
<p>All SNPs with <i>P</i><10<sup>−5</sup> are represented by the lowest <i>P</i>-value for the avera...
<p>The strength of association for known (bottom) and unknown (top) metabolites is indicated as the ...
<p>The values in the map are the normalized measures of allelic association |D’| (<b>A</b>) and corr...
<p>Combined association scores were computed using Mantel Haenszel X<sup>2</sup> test, following imp...
<p><b>(A)</b> The heatmap above indicates LD distribution. The color density represents the average ...
We estimated the median size of genomic regions with pronounced linkage at F20 by the autocorrelatio...
A major finding from the last decade of genome-wide association studies (GWAS) is that variant-pheno...
<p>All SNPs from single marker analyses with a nominal <i>P</i><10<sup>−5</sup> are shown. Associati...
<p>Manhattan plots and accompanying linkage disequilibrium heat maps are depicted for the (A) <i>e r...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...
<p>the y axis represents–log<sub>10</sub> (p values) and the x axis shows position within <i>MUC5B</...
<p>Panels on the left are regional association plots for all variants in the MHC region; each diamon...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...
<p>(<b>A</b>) Manhattan-plot showing the negative decadic logarithms of the raw P values obtained fr...
<p>The strengths of genome-wide association studies (GWAS) are illustrated by the Manhattan plots on...
<p>All SNPs with <i>P</i><10<sup>−5</sup> are represented by the lowest <i>P</i>-value for the avera...
<p>The strength of association for known (bottom) and unknown (top) metabolites is indicated as the ...
<p>The values in the map are the normalized measures of allelic association |D’| (<b>A</b>) and corr...
<p>Combined association scores were computed using Mantel Haenszel X<sup>2</sup> test, following imp...
<p><b>(A)</b> The heatmap above indicates LD distribution. The color density represents the average ...
We estimated the median size of genomic regions with pronounced linkage at F20 by the autocorrelatio...
A major finding from the last decade of genome-wide association studies (GWAS) is that variant-pheno...