<p>(A) Average steady-state input resistance as a function of membrane voltage. Measures were taken in voltage-clamp using a 100 ms duration 5 mV step. (B) Average membrane voltage trajectory (grey lines indicate SEM) associated with approach from rest to first spike. For comparison, the exponential approximation using the membrane time constant measures taken at -75 mV is also shown. (C) Average membrane voltage trajectory (grey lines indicate SEM) associated with the interspike interval. (D) Representative example of an <i>f-V</i> curve from a stellate cell (solid line). Line indicates fit to a power-law function of the form shown in panel inset. Inset also shows box-plot of mean exponent (<i>p</i>) value for the power-law function fit.</...
<p>(A), recording of resting membrane potential, showing spontaneous action potential firing at 18.1...
<p>A) Spike height and width: The blue trace represents the original voltage data with small blue ma...
The presence of voltage fluctuations arising from synaptic activity is a critical component in model...
<p>(A) Average membrane voltage trajectories for initial spike approach in stellate cells under -5 n...
<p>(A) Plot of <i>I-V</i> curves from eLIF models using different Δ<sub><i>T</i></sub> (2, 5, 15 mV)...
<p>(A) Plot of average stellate cell <i>f-I</i> curves using -5 ns (red), control (black) and 15 nS ...
<p>(A) Steady-state membrane input resistance measures for different holding voltages under control ...
<p>(A): Timing of onset of clamp pulses during different phases of the TNNP ventricle model AP are i...
<p>The optimization results for all cells are shown for three parameters: high voltage slope (<b>a<...
A change in the holding voltage, exposure to channel-blocking agents, and similar interventions will...
<p>(A) Example traces of eLIF models implemented with Δ<sub><i>T</i></sub> = 15 mV (i) and 2 mV (ii)...
<p>A) Intracellular recordings of 1) a cell with a positive oscillation (MPSO+), 2) a cell with a ne...
<p>A) An Example of a membrane potential trace from the LP model with gray bars indicating timing of...
<p>(A) The membrane voltage in response to the 50 ms noise burst. Arrows indicate the fast inhibitio...
<p>A: At equivalent membrane potentials, the subthreshold membrane oscillations of NVmes cells expos...
<p>(A), recording of resting membrane potential, showing spontaneous action potential firing at 18.1...
<p>A) Spike height and width: The blue trace represents the original voltage data with small blue ma...
The presence of voltage fluctuations arising from synaptic activity is a critical component in model...
<p>(A) Average membrane voltage trajectories for initial spike approach in stellate cells under -5 n...
<p>(A) Plot of <i>I-V</i> curves from eLIF models using different Δ<sub><i>T</i></sub> (2, 5, 15 mV)...
<p>(A) Plot of average stellate cell <i>f-I</i> curves using -5 ns (red), control (black) and 15 nS ...
<p>(A) Steady-state membrane input resistance measures for different holding voltages under control ...
<p>(A): Timing of onset of clamp pulses during different phases of the TNNP ventricle model AP are i...
<p>The optimization results for all cells are shown for three parameters: high voltage slope (<b>a<...
A change in the holding voltage, exposure to channel-blocking agents, and similar interventions will...
<p>(A) Example traces of eLIF models implemented with Δ<sub><i>T</i></sub> = 15 mV (i) and 2 mV (ii)...
<p>A) Intracellular recordings of 1) a cell with a positive oscillation (MPSO+), 2) a cell with a ne...
<p>A) An Example of a membrane potential trace from the LP model with gray bars indicating timing of...
<p>(A) The membrane voltage in response to the 50 ms noise burst. Arrows indicate the fast inhibitio...
<p>A: At equivalent membrane potentials, the subthreshold membrane oscillations of NVmes cells expos...
<p>(A), recording of resting membrane potential, showing spontaneous action potential firing at 18.1...
<p>A) Spike height and width: The blue trace represents the original voltage data with small blue ma...
The presence of voltage fluctuations arising from synaptic activity is a critical component in model...