<p>The optimization results for all cells are shown for three parameters: high voltage slope (<b>a</b>), low voltage slope (<b>b</b>) and time constant (<b>c</b>). Blue bars correspond to mean ± standard deviation over all recordings categorized by average membrane potential, and red bars (when available) correspond to mean ± standard deviation over all recordings categorized by stimulus condition (e.g. varying ITD with fixed IID). <b>d</b>, Distribution of average distance within cells between steady-state threshold functions (grey) and between steady-state threshold functions and the diagonal (green). <b>e</b>, Distribution of false alarm rates when the models are tested against recordings with a different mean (blue) and with differe...
<p>After fitting, we see (A) the removal of the spike-related kernel through the difference between ...
<p><b>A,</b> Three different action potentials during the rising phase. Vertical arrows depict the p...
<p>(A) Spike triggered average voltage for and firing rates ; simulated results (circles) and anal...
<p><b>a</b>, Top: voltage trace (top, black) and predicted threshold (red). Bottom: steady-state thr...
<p>A) Spike height and width: The blue trace represents the original voltage data with small blue ma...
<p>(A) Average steady-state input resistance as a function of membrane voltage. Measures were taken ...
<p>A. Double somatic whole-cell patch-clamp recording from a representative Purkinje cell: one elect...
<p>(a) The increase in spike probability with increasing amplitude of the standard deviation of the ...
<p>(A) Example traces of eLIF models implemented with Δ<sub><i>T</i></sub> = 15 mV (i) and 2 mV (ii)...
<p>To show that the optimized threshold time constant (about 260 µs on average) is accurate, we fitt...
<p>Left two columns: reliability (coincidence factor Γ or Hunter and Milton measure <i>R</i><sub><i>...
<p>a, The critical voltage <i>V</i><sub><i>c</i></sub> in pyramidal neurons was determined as a fit ...
<p>A set of sample spikes from Type I and Type II neuron as d<i>V</i>/d<i>t</i> increases from 0.2mV...
<p>(A) Stochastic stimulation optimization sequence shows the difference between the experimental vo...
<p><b>A,</b> Three action potentials (clipped) recorded from a TRN neuron are shown with the membran...
<p>After fitting, we see (A) the removal of the spike-related kernel through the difference between ...
<p><b>A,</b> Three different action potentials during the rising phase. Vertical arrows depict the p...
<p>(A) Spike triggered average voltage for and firing rates ; simulated results (circles) and anal...
<p><b>a</b>, Top: voltage trace (top, black) and predicted threshold (red). Bottom: steady-state thr...
<p>A) Spike height and width: The blue trace represents the original voltage data with small blue ma...
<p>(A) Average steady-state input resistance as a function of membrane voltage. Measures were taken ...
<p>A. Double somatic whole-cell patch-clamp recording from a representative Purkinje cell: one elect...
<p>(a) The increase in spike probability with increasing amplitude of the standard deviation of the ...
<p>(A) Example traces of eLIF models implemented with Δ<sub><i>T</i></sub> = 15 mV (i) and 2 mV (ii)...
<p>To show that the optimized threshold time constant (about 260 µs on average) is accurate, we fitt...
<p>Left two columns: reliability (coincidence factor Γ or Hunter and Milton measure <i>R</i><sub><i>...
<p>a, The critical voltage <i>V</i><sub><i>c</i></sub> in pyramidal neurons was determined as a fit ...
<p>A set of sample spikes from Type I and Type II neuron as d<i>V</i>/d<i>t</i> increases from 0.2mV...
<p>(A) Stochastic stimulation optimization sequence shows the difference between the experimental vo...
<p><b>A,</b> Three action potentials (clipped) recorded from a TRN neuron are shown with the membran...
<p>After fitting, we see (A) the removal of the spike-related kernel through the difference between ...
<p><b>A,</b> Three different action potentials during the rising phase. Vertical arrows depict the p...
<p>(A) Spike triggered average voltage for and firing rates ; simulated results (circles) and anal...