Effects of TG and TM on cell viability in MDR lung cancer cells.

<p>(A) Parental A549 and A549/D16 cells (2×10⁴ cells/well) were treated with various concentrations of TG with DOC (16 nM) or without DOC for 48 h for drug sensitivity measurements. Similar conditions were applied to (B) A549 and A549/V16 cells with VCR (16 nM). (C) Parental A549 and A549/D16 cells were treated with various concentrations of TM with DOC or without DOC for 48 h for drug sensitivity measurements. Similar conditions were applied to (D) A549 and A549/V16 cells. (E) A549/D16 cells were pre-treated with VER (0, 0.5, 1, 2 and 4 μM) for 2 h followed by various concentrations of TG for 48 h. Cell viability was analyzed on MTT assay.