<p><b>A.</b> The structures and chemical names of TM5275 and TM5441 are shown. <b>B.</b> The indicated cell lines were treated with increasing concentrations of TM5275 (black) or TM5441 (red). Viability was measured by relative luminescence units for increasing concentrations of TM5275 and TM5441 and were graphed as % survival (± SD) in comparison to DMSO control treated cells. Data was plotted and a best fit line was drawn, n = 3.</p
This article was published in the Fall 2009 issue of the Journal of Undergraduate Researc
<p>(A) Structures of lead compounds TP187, 197 and 421. (B) Colony formation assay was performed usi...
<p>The cells were cultured on glass substrates for 24μM of DMSO or blebbistatin for 1 hour (<i>n</i>...
<p>Viability was measured after 45% of vehicle (0.05% DMSO)-treated control. For comparison, the leu...
<p><b>A</b>. Caspase 3/7 activity of HT1080 and HCT116 cells treated with increasing concentrations ...
<p>Representative fluorescence-activated cell sorting (FACS) plots are shown in the upper panels wit...
<p>(A) The chemical structure of <b>1d</b>. (B) Cells were treated with <b>1d</b> at 5 or 10 μg/ml o...
<p>Representative images of (A) U87-MG and U–SC, and (B) L0627 morphology after 48 h treatment with ...
<p>The viability curves of B cells and PBMCs after four days of incubation with different concentrat...
<p>(A) Chemical structure of IMB5043. (B) IC<sub>50</sub> of IMB5043 in various cancer cells. Cells ...
<p><b>A</b>) Cells (5×10<sup>3</sup> cells/well) were seeded in 96-well plates and treated with incr...
<p>(A) Parental A549 and A549/D16 cells (2×10<sup>4</sup> cells/well) were treated with various conc...
<p>(A) The viability of lung adenocarcinoma CL1–5 cells cultured with various concentrations of DMSO...
<p>Normal (HaCaT) and tumor cells (HeLa, T98G and U118)were treated with different TMZ concentration...
This article was published in the Fall 2009 issue of the Journal of Undergraduate Researc
This article was published in the Fall 2009 issue of the Journal of Undergraduate Researc
<p>(A) Structures of lead compounds TP187, 197 and 421. (B) Colony formation assay was performed usi...
<p>The cells were cultured on glass substrates for 24μM of DMSO or blebbistatin for 1 hour (<i>n</i>...
<p>Viability was measured after 45% of vehicle (0.05% DMSO)-treated control. For comparison, the leu...
<p><b>A</b>. Caspase 3/7 activity of HT1080 and HCT116 cells treated with increasing concentrations ...
<p>Representative fluorescence-activated cell sorting (FACS) plots are shown in the upper panels wit...
<p>(A) The chemical structure of <b>1d</b>. (B) Cells were treated with <b>1d</b> at 5 or 10 μg/ml o...
<p>Representative images of (A) U87-MG and U–SC, and (B) L0627 morphology after 48 h treatment with ...
<p>The viability curves of B cells and PBMCs after four days of incubation with different concentrat...
<p>(A) Chemical structure of IMB5043. (B) IC<sub>50</sub> of IMB5043 in various cancer cells. Cells ...
<p><b>A</b>) Cells (5×10<sup>3</sup> cells/well) were seeded in 96-well plates and treated with incr...
<p>(A) Parental A549 and A549/D16 cells (2×10<sup>4</sup> cells/well) were treated with various conc...
<p>(A) The viability of lung adenocarcinoma CL1–5 cells cultured with various concentrations of DMSO...
<p>Normal (HaCaT) and tumor cells (HeLa, T98G and U118)were treated with different TMZ concentration...
This article was published in the Fall 2009 issue of the Journal of Undergraduate Researc
This article was published in the Fall 2009 issue of the Journal of Undergraduate Researc
<p>(A) Structures of lead compounds TP187, 197 and 421. (B) Colony formation assay was performed usi...
<p>The cells were cultured on glass substrates for 24μM of DMSO or blebbistatin for 1 hour (<i>n</i>...