<p>A) Power as a function of contamination proportion. B) Power as a function of study size. C) Power as a function of the genetic effect size. (Simulation parameters: 10000 samples; A, B and D: N = 100; B, C and D:<i>π</i> = 0.95)</p
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>Power simulating results of PCA-based MPPAS using , , and statistics under various sample sizes...
Power to detect genetic and environmental influences increases not only with sample size but also wi...
Statistical power calculations constitute an essential first step in the planning of scientific stud...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
The power of a statistical test is the probability that it will yield a statistically significant re...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
1. ‘Will my study answer my research question? ’ is the most fundamental question a researcher can a...
<p>The <i>Latent</i> column is the power with the proposed method applied to 6 latent phenotypes. Th...
<p>Measurement error is displayed in terms of the number of SD of the true phenotype (without errors...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>Power simulating results of PCA-based MPPAS using , , and statistics under various sample sizes...
Power to detect genetic and environmental influences increases not only with sample size but also wi...
Statistical power calculations constitute an essential first step in the planning of scientific stud...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
The power of a statistical test is the probability that it will yield a statistically significant re...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
1. ‘Will my study answer my research question? ’ is the most fundamental question a researcher can a...
<p>The <i>Latent</i> column is the power with the proposed method applied to 6 latent phenotypes. Th...
<p>Measurement error is displayed in terms of the number of SD of the true phenotype (without errors...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>In the first row, we compare power of the three methods for different values of heritability unde...
<p>In the first row, we compare power of the three methods for different values of heritability unde...