Mouse and human HCC clustering.

<p>the gene expression data of the human HCC of mixed etiologies has been integrated with HCC samples from GNMT and MAT1A mouse KO models of HCC derived from NAFLD by selecting the orthologous genes using the homologene database. The integrated data holds 1691 genes obtained from matching the orthologous genes between the genes having at least 9 samples of two fold regulation in the human HCC series, the 15 month MAT1A KO and 8 month GNMT mouse KO models. Using complete hierarchical clustering and Pearson correlation it is possible to distinguish cluster A and B with significant differences of survival length and the mouse models laying together cluster A.