<p>Experimental data shown by open circles (average temperature); error bars represent standard deviations over a group of rats. Model responses using best fit parameters are shown as a thick lines. SB vehicles for both doses were pooled into a single group. Columns of graphs correspond to different doses of the antagonist (A-D: Vehicle, E-H: 10 mg/kg and I-K: 30 mg/kg as marked at the top), rows of graphs correspond to different doses of Meth (Saline, 1, 5 and 10 mg/kg, as marked at the left).</p
<p>(<i>A</i>) Bayesian Information Criterion scores for each model (a low score is better). Models b...
<p>Comparison of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood ...
(A) Example of how the models fit to the data from the liver from one of the rats. (B-D) Correlation...
(A, D) show the estimated ki and kef grouped by drug dose. (B, E) show dose-response plots for ki an...
<p>A-B: Statistical ensembles of parameters (amplitude of stress, and Meth-sensitivities of three Me...
<p>All drugs were administered for 1.5 h during the treatment period. Values are presented as means,...
<p>Graphical analysis of model fit comparing behavioural (empirical) and model (predicted) data. Dat...
<p>The data points are from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.01...
<p>(A) Schematic diagram for the dual-state model. (B–C) Cumulative ICI distributions of the empiric...
The vertical dashed line represents the overall effect size. Filled circles represent experiments fr...
<p>A-D: Activity of the network nodes as functions of Meth concentration in the blood after three do...
Orexinergic neurotransmission is involved in mediating temperature responses to methamphetamine (Met...
<p>Grey lines represent the median used to compute proportions of high and low scores in good and po...
(A) Comparison of the searching distance in the place navigation test; (B) Comparison of the swimmin...
<p>The calibrated model shows good agreement between model simulations (black) and experimental BW (...
<p>(<i>A</i>) Bayesian Information Criterion scores for each model (a low score is better). Models b...
<p>Comparison of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood ...
(A) Example of how the models fit to the data from the liver from one of the rats. (B-D) Correlation...
(A, D) show the estimated ki and kef grouped by drug dose. (B, E) show dose-response plots for ki an...
<p>A-B: Statistical ensembles of parameters (amplitude of stress, and Meth-sensitivities of three Me...
<p>All drugs were administered for 1.5 h during the treatment period. Values are presented as means,...
<p>Graphical analysis of model fit comparing behavioural (empirical) and model (predicted) data. Dat...
<p>The data points are from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.01...
<p>(A) Schematic diagram for the dual-state model. (B–C) Cumulative ICI distributions of the empiric...
The vertical dashed line represents the overall effect size. Filled circles represent experiments fr...
<p>A-D: Activity of the network nodes as functions of Meth concentration in the blood after three do...
Orexinergic neurotransmission is involved in mediating temperature responses to methamphetamine (Met...
<p>Grey lines represent the median used to compute proportions of high and low scores in good and po...
(A) Comparison of the searching distance in the place navigation test; (B) Comparison of the swimmin...
<p>The calibrated model shows good agreement between model simulations (black) and experimental BW (...
<p>(<i>A</i>) Bayesian Information Criterion scores for each model (a low score is better). Models b...
<p>Comparison of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood ...
(A) Example of how the models fit to the data from the liver from one of the rats. (B-D) Correlation...