Representative size exclusion profiles of [¹⁴C]RSA in urine collected after intravenous administration in PAN (<i>closed circles</i>) and control (<i>open circles</i>) rats.

<p>The same levels of radioactivity in the urine of PAN and controls was loaded onto the column. Identical profiles were obtained at 2 h and 24 h (from <i>n</i> = 5 for each time point). Native [¹⁴C]RSA elutes at Kav 0.18. Chromatography was performed on Sephadex G-100.