Inhibition of the Metabolic Degradation of Filtered Albumin Is a Major Determinant of Albuminuria - Fig 2

<p><b>(A)</b> Representative size exclusion profile of [¹⁴C]RSA in urine (<i>closed squares</i>). The profiles of urine collected at 0.5 h, 1 h and 2h were identical. For each time point <i>n</i> = 5. Dotted line represents native [¹⁴C]RSA (<i>open squares</i>). <b>(B)</b> Representative size exclusion profile of [¹⁴C]RSA in plasma (<i>closed circles</i>). Identical profiles were obtained at 15 min, 30 min, 1 h, 2 h, 24 h and 168 h after intravenous administration in rats. For each time point <i>n</i> = 5 to 7. Dotted line represents native [¹⁴C]RSA (<i>open circles</i>). Chromatography was performed on Sephadex G-100.