Inhibition of the Metabolic Degradation of Filtered Albumin Is a Major Determinant of Albuminuria - Fig 5

<p><b>(A)</b> Tissue distribution of radioactivity at various times after administration of [¹⁴C]RSA (at 1, 4, 24 and 168 h) or [³H]RSA (at 0.25 h). <b>(B)</b> Tissue to plasma ratio of radioactivity at various times after intravenous administration of [¹⁴C]RSA or [³H]RSA. Tissue to plasma ratio was calculated as [(Bq/g tissue)/(Bq/ml plasma)]. For all tissues <b>(A & B)</b>, <i>n</i> = 5 at each time point. Values are expressed as percentage of the injected dose, assuming total blood volume equals 7% of the body weight, total muscle mass equals 25% of the body weight and total liver mass equals 2.5% of body weight. Tissue to plasma ratio was calculated as [(dpm/g tissue)/(dpm/ml plasma)].