<p>Panels a-d depict data from three eligible animals (one from group A with perfusate A and two from group B with anti-inflammatory perfusate B). Data are displayed as individual measurements per time interval. RD<sub>urea</sub> (%) was expressed as median (min-max) of values obtained on day 4. Symbols denote: *p<0.05 and **p<0.01 <i>vs</i>. rat A. Statistical approach was restricted to the evaluation of inter-individual differences owing to low number of subjects. Possible effect of 5-ASA (perfusate B) could not be determined. Due to ethical reasons the attempts to harvest more data were discontinued.</p
<p>In these protocols data were obtained in the same rats during baseline conditions and during insu...
<p>Data refers to wet organ mass and its ratio to body mass was obtained dividing the organ mass ove...
<p>(a) The outline of animal test. (b) The body weights of rats were measured randomly at day 0, 3, ...
<p>Mean concentrations (nM) and standard deviations between the rats (see <a href="http://www.ploson...
Microdialysis has contributed with very important knowledge to the understanding of target-specific ...
Sensors able to record large bowel physiology and biochemistry in situ in awake rodents are lacking....
<p>(A) <i>In vivo</i> rat PK comparison of non-PEGylated (blue triangles), di-PEGylated uricase (bla...
<p>Median values with 25th–75th percentiles. Energy related metabolites (upper) and Lactate/Pyruvate...
<div><p>Sensors able to record large bowel physiology and biochemistry <i>in situ</i> in awake roden...
A database of micronuclei counts for historical negative control data from rat in vivo micronuclei t...
<p>Data presented as means ± SD (n = 5).</p><p><sup>a</sup> indicates a significant difference compa...
<p>The number of surviving mice in non-diabetic groups (top left panel) and in diabetics groups (top...
Assuming that temporal fluctuations in physiological parameters (e.g. haematology, biochemistry) in ...
<p>(A) Urea, (B) creatinine, (C) calcium and (D) phosphorus levels and (E) alkaline phosphatase acti...
<p>Empty circles denote probe in urine following oral administration; filled circles represent probe...
<p>In these protocols data were obtained in the same rats during baseline conditions and during insu...
<p>Data refers to wet organ mass and its ratio to body mass was obtained dividing the organ mass ove...
<p>(a) The outline of animal test. (b) The body weights of rats were measured randomly at day 0, 3, ...
<p>Mean concentrations (nM) and standard deviations between the rats (see <a href="http://www.ploson...
Microdialysis has contributed with very important knowledge to the understanding of target-specific ...
Sensors able to record large bowel physiology and biochemistry in situ in awake rodents are lacking....
<p>(A) <i>In vivo</i> rat PK comparison of non-PEGylated (blue triangles), di-PEGylated uricase (bla...
<p>Median values with 25th–75th percentiles. Energy related metabolites (upper) and Lactate/Pyruvate...
<div><p>Sensors able to record large bowel physiology and biochemistry <i>in situ</i> in awake roden...
A database of micronuclei counts for historical negative control data from rat in vivo micronuclei t...
<p>Data presented as means ± SD (n = 5).</p><p><sup>a</sup> indicates a significant difference compa...
<p>The number of surviving mice in non-diabetic groups (top left panel) and in diabetics groups (top...
Assuming that temporal fluctuations in physiological parameters (e.g. haematology, biochemistry) in ...
<p>(A) Urea, (B) creatinine, (C) calcium and (D) phosphorus levels and (E) alkaline phosphatase acti...
<p>Empty circles denote probe in urine following oral administration; filled circles represent probe...
<p>In these protocols data were obtained in the same rats during baseline conditions and during insu...
<p>Data refers to wet organ mass and its ratio to body mass was obtained dividing the organ mass ove...
<p>(a) The outline of animal test. (b) The body weights of rats were measured randomly at day 0, 3, ...