Loss of striatal protein TH and increased dopamine turnover after MPTP treatment.

<p>Protein blots for striatal TH were analyzed TH/β-actin ratio and normalized by the results of CON (A, B). Dopamine turnover, which was analyzed by DOPAC/DA and HVA/DA ratio, exhibited significant increase after MPTP treatment (C). Data are presented as mean±SEM of 3 mice; *, compared to CON; #, compared to SYN; +, compared to MPTP. *, +, #: <i>P</i><0.05; **, ++, ##: <i>P</i><0.01; ***, ###, +++: <i>P</i><0.001 (one-way ANOVA Newman-Keuls <i>post-hoc</i> test).