<p>A. Bar graph of averaged binding ratios from 3 independent screenings. Error bar indicates the standard deviation (n = 3). The red line indicates the average binding ratio obtained after addition of DMSO and GTP (= 0.390). The white arrow indicates the chemical that most effectively inhibited FtsZ dimerization. B. The Venn diagram shows a summary of the 1st screening by FCCS.</p
<p>One PPARγ full agonist (Rosiglitazone) and one partial agonist (FMOC) were also assayed. Error ba...
<p>(A) Plate layout for screening BSH inhibitors. Pink boxes (columns 3–22) indicate test wells that...
<p>Preliminary hit clustering was based on the EC50 value from the concentration-response curves of ...
<p>A. Bar graph of averaged binding ratios of 3 independent screenings. Error bar indicates the stan...
<p>A. When a chemical has an inhibitory effect on FtsZ dimerization even in the presence of GTP, the...
<p>(A) Compounds screened ranked by percent inhibition and normalized to negative and positive contr...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
<p>The chemicals are numbered from #1 to #6 in order of the inhibition % calculated from FCCS analys...
<p>A) Alterations in cell number A) after 24 (open squares) or 48 hours exposure (closed triangles) ...
<p>Scatter plot of screening data for a small library of known bioactive small molecules using the P...
<p>(A) Layout of microplate. Wells marked in green are CXCR4 inhibitors. Controls are shown in white...
<p>Compounds with >40% activity against either <i>Ldon</i> [red], <i>Pfal</i> [yellow] or both NMT t...
<p>The chart represents the averaged inhibitory percentage with error bars representing standard dev...
<p>Merged images for nucleus, PV and amastigote fluorescence of one acquisition field representing d...
The “RIKEN” screen consisted of 8418 total compounds from the RIKEN Natural Product Depository, and ...
<p>One PPARγ full agonist (Rosiglitazone) and one partial agonist (FMOC) were also assayed. Error ba...
<p>(A) Plate layout for screening BSH inhibitors. Pink boxes (columns 3–22) indicate test wells that...
<p>Preliminary hit clustering was based on the EC50 value from the concentration-response curves of ...
<p>A. Bar graph of averaged binding ratios of 3 independent screenings. Error bar indicates the stan...
<p>A. When a chemical has an inhibitory effect on FtsZ dimerization even in the presence of GTP, the...
<p>(A) Compounds screened ranked by percent inhibition and normalized to negative and positive contr...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
<p>The chemicals are numbered from #1 to #6 in order of the inhibition % calculated from FCCS analys...
<p>A) Alterations in cell number A) after 24 (open squares) or 48 hours exposure (closed triangles) ...
<p>Scatter plot of screening data for a small library of known bioactive small molecules using the P...
<p>(A) Layout of microplate. Wells marked in green are CXCR4 inhibitors. Controls are shown in white...
<p>Compounds with >40% activity against either <i>Ldon</i> [red], <i>Pfal</i> [yellow] or both NMT t...
<p>The chart represents the averaged inhibitory percentage with error bars representing standard dev...
<p>Merged images for nucleus, PV and amastigote fluorescence of one acquisition field representing d...
The “RIKEN” screen consisted of 8418 total compounds from the RIKEN Natural Product Depository, and ...
<p>One PPARγ full agonist (Rosiglitazone) and one partial agonist (FMOC) were also assayed. Error ba...
<p>(A) Plate layout for screening BSH inhibitors. Pink boxes (columns 3–22) indicate test wells that...
<p>Preliminary hit clustering was based on the EC50 value from the concentration-response curves of ...