The “RIKEN” screen consisted of 8418 total compounds from the RIKEN Natural Product Depository, and the “NCI/NIH/GSK” screen consisted of 3565 compounds across 6 chemical compound collections from the National Cancer Institute, National Institutes of Health, and GlaxoSmithKline.</p
High-throughput screening (HTS) is the primary technique for new lead identification in drug discove...
A two-dimensional gas chromatography-time-of-flight/mass spectrometry (GC×GC-TOF/MS) suspect screeni...
At the dawn of the 21st century, human genetic sequencing in combination with computationally-enable...
Perturbed bioprocesses were predicted using CG-TARGET for compounds, experimental controls (DMSO), a...
Perturbed bioprocesses were predicted using both CG-TARGET and a method that calculated enrichment o...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
Chemical-genetic interaction profiles and their corresponding importance score profiles (see Fig 4 l...
<p>Compound counts are unique chemical structures for the specified source or source combination. Al...
In lead discovery, libraries of 106 molecules are screened for biological activity. Given the over 1...
Chemical-genetic interactions–observed when the treatment of mutant cells with chemical compounds re...
<p>A. Bar graph of averaged binding ratios from 3 independent screenings. Error bar indicates the st...
International audienceHigh-throughput screening assays have become the starting point of many drug d...
†<p>18,432 compounds from Maybridge HitFinder Collection; 1,150 compounds from NIH Clinical Collecti...
<p>The list of compounds that overlapped between the two technologies, which was 18 out of a possibl...
<p><b>A</b>) Venn diagram with common compounds with predictions from the three different approaches...
High-throughput screening (HTS) is the primary technique for new lead identification in drug discove...
A two-dimensional gas chromatography-time-of-flight/mass spectrometry (GC×GC-TOF/MS) suspect screeni...
At the dawn of the 21st century, human genetic sequencing in combination with computationally-enable...
Perturbed bioprocesses were predicted using CG-TARGET for compounds, experimental controls (DMSO), a...
Perturbed bioprocesses were predicted using both CG-TARGET and a method that calculated enrichment o...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
Chemical-genetic interaction profiles and their corresponding importance score profiles (see Fig 4 l...
<p>Compound counts are unique chemical structures for the specified source or source combination. Al...
In lead discovery, libraries of 106 molecules are screened for biological activity. Given the over 1...
Chemical-genetic interactions–observed when the treatment of mutant cells with chemical compounds re...
<p>A. Bar graph of averaged binding ratios from 3 independent screenings. Error bar indicates the st...
International audienceHigh-throughput screening assays have become the starting point of many drug d...
†<p>18,432 compounds from Maybridge HitFinder Collection; 1,150 compounds from NIH Clinical Collecti...
<p>The list of compounds that overlapped between the two technologies, which was 18 out of a possibl...
<p><b>A</b>) Venn diagram with common compounds with predictions from the three different approaches...
High-throughput screening (HTS) is the primary technique for new lead identification in drug discove...
A two-dimensional gas chromatography-time-of-flight/mass spectrometry (GC×GC-TOF/MS) suspect screeni...
At the dawn of the 21st century, human genetic sequencing in combination with computationally-enable...