<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle for 35 days. The levels of serum glucose (A, B) were determined by blood glucose test strips, while the levels of urine glucose (C) and serum glucose (D) were tested by biochemical methods. Data were expressed as means ± S.D.; *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 were compared with model group, analyzed by one way ANOVA and the Fisher’s PLSD.</p
<p>(A, D) No significant change was observed on blood glucose levels during the OGTT between vehicle...
<p>Glucokinase specific activity at different glucose concentrations (range 0–20 mmol/l) in mice 2 h...
<p>The indicated doses of novel compounds (codes and chemical structures shown above the bar graphs)...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>NOTE: Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or ve...
<p>Light microscopy 400×. Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 ...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>Light microscopy 200×. Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 ...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>(<b>A</b>) Intraperitoneal glucose tolerant test in mice treated with vehicle or BPA. Plasma gluc...
<p>(A) Blood glucose levels were measured in overnight-fasted female <i>db/db</i> mice (n = 9–10 per...
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>(<b>A</b>) RBG was examined weekly during ZBPYR administration. ZBPYR significantly reduced gluco...
<p>BDDE was administered orally to db/db mice once a day for 4 weeks. The blood glucose (A), HbA1c l...
<p>(A, D) No significant change was observed on blood glucose levels during the OGTT between vehicle...
<p>Glucokinase specific activity at different glucose concentrations (range 0–20 mmol/l) in mice 2 h...
<p>The indicated doses of novel compounds (codes and chemical structures shown above the bar graphs)...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>NOTE: Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or ve...
<p>Light microscopy 400×. Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 ...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>Light microscopy 200×. Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 ...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>Diabetic mice were treated with BPs (30 and 60 mg/kg/day), glyburide (7.2 mg/kg/day), or vehicle ...
<p>(<b>A</b>) Intraperitoneal glucose tolerant test in mice treated with vehicle or BPA. Plasma gluc...
<p>(A) Blood glucose levels were measured in overnight-fasted female <i>db/db</i> mice (n = 9–10 per...
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>(<b>A</b>) RBG was examined weekly during ZBPYR administration. ZBPYR significantly reduced gluco...
<p>BDDE was administered orally to db/db mice once a day for 4 weeks. The blood glucose (A), HbA1c l...
<p>(A, D) No significant change was observed on blood glucose levels during the OGTT between vehicle...
<p>Glucokinase specific activity at different glucose concentrations (range 0–20 mmol/l) in mice 2 h...
<p>The indicated doses of novel compounds (codes and chemical structures shown above the bar graphs)...