Immunization with MAP27 promoted IFN-γ, IL-17A/F and CCL3 production in organs post infection with <i>S</i>. <i>aureus</i>.

<p>Five days after boosting with heat-inactivated <i>S</i>. <i>aureus</i>, all of the mice (n = 5 mice per group) were infected with <i>S</i>. <i>aureus</i> (2×10⁷ CFU/mouse) for three days. Spleen and lung were aseptically taken and homogenized with sterile PBS. The supernatants were pooled and analyzed by ELISA. The concentrations of IFN-γ (panel A and D), IL-17A/F (panel B and E), and chemokine ligand 3 (CCL3, panel C and F) were measured in spleen and lung, respectively. * P<0.05, ** P<0.01, *** P<0.001.