Inflammatory cytokine production in mice immunized with 2OA-BSA.

<p>(A) Serum levels of IL-17A, IFN-γ, TNF-α and IL-6 in WT, IL-17A^−/−, IL-17F^−/− and IL-22^−/− mice, respectively, at 2 weeks following 2OA-BSA immunization. (B) Production of IFN-γ in supernatant fluids of cultured splenic and hepatic MNCs (n = 4) with anti-CD3/CD28 mAbs at 3 days. (C) The level of inflammatory cytokines in extracted liver protein from WT, IL-17A^−/−, IL-17F^−/− and IL-22^−/− mice, respectively. Each group n = 8. *p&lt;0.05, **p&lt;0.01, ***p&lt;0.001.