Showing SE alleles in HLA-DRB1 in relation to achieving DMARD-free sustained remission in RA patients in the Leiden EAC cohort. SE alleles were significantly associated with achieving DMARD-free sustained remission in 616 RA patients with HLA-DRB1 genotyping data (p = 2.72 × 10−4). The HR per SE allele for achieving remission was 0.57 (95 % CI = 0.42–0.77). The analysis was adjusted for age, gender, and inclusion period (as proxy for treatment strategy). (PDF 52 kb
Significant single nucleotide polymorphism (SNP) variants associated with anti-HCP1 positivity in pa...
Presenting associations between each of the 76 SNPs and EULAR response. (DOCX 37 kb
Correlation of n-cirDNA, m-cirDNA, n-csbDNA, m-csbDNA, ACPA, CRP, and RF between each other and with...
Showing genetic variants in relation to achieving DMARD-free sustained remission in ACPA-positive an...
Figure S1. Agreement between previously determined antibody status and remeasurement by ELISA. Figu...
Figure S1. Comparison of longer and shorter CD4+ T cell activation timecourses. Figure S2. Summary d...
Figure S2. Kaplan–Meier survival curve for maintaining bDMARD-free remission after discontinuation o...
Regional plots showing association results from GEE models at 6q15, 6q27 and 10q25.3, when the analy...
Clinical features of studied groups of patients with RA and healthy controls. Table S2 The expressio...
Conditional logistic regression analysis between the protective HLA alleles in AOSD. (PDF 43 kb
International audienceIntroduction: Although rheumatoid arthritis (RA) is generally a chronic diseas...
Supplementary methods. Figure S1. DAS44 over time. Table S1. Baseline characteristics of patients wh...
Correlation of n-cirDNA, m-cirDNA, n-csbDNA, m-csbDNA, ACPA, CRP, and RF between each other and with...
Presenting associations between GRS SNPs and baseline clinical characteristics. (DOCX 18 kb
Table S1. Univariate logistic regression analysis for associated factors to predict ACR20 response a...
Significant single nucleotide polymorphism (SNP) variants associated with anti-HCP1 positivity in pa...
Presenting associations between each of the 76 SNPs and EULAR response. (DOCX 37 kb
Correlation of n-cirDNA, m-cirDNA, n-csbDNA, m-csbDNA, ACPA, CRP, and RF between each other and with...
Showing genetic variants in relation to achieving DMARD-free sustained remission in ACPA-positive an...
Figure S1. Agreement between previously determined antibody status and remeasurement by ELISA. Figu...
Figure S1. Comparison of longer and shorter CD4+ T cell activation timecourses. Figure S2. Summary d...
Figure S2. Kaplan–Meier survival curve for maintaining bDMARD-free remission after discontinuation o...
Regional plots showing association results from GEE models at 6q15, 6q27 and 10q25.3, when the analy...
Clinical features of studied groups of patients with RA and healthy controls. Table S2 The expressio...
Conditional logistic regression analysis between the protective HLA alleles in AOSD. (PDF 43 kb
International audienceIntroduction: Although rheumatoid arthritis (RA) is generally a chronic diseas...
Supplementary methods. Figure S1. DAS44 over time. Table S1. Baseline characteristics of patients wh...
Correlation of n-cirDNA, m-cirDNA, n-csbDNA, m-csbDNA, ACPA, CRP, and RF between each other and with...
Presenting associations between GRS SNPs and baseline clinical characteristics. (DOCX 18 kb
Table S1. Univariate logistic regression analysis for associated factors to predict ACR20 response a...
Significant single nucleotide polymorphism (SNP) variants associated with anti-HCP1 positivity in pa...
Presenting associations between each of the 76 SNPs and EULAR response. (DOCX 37 kb
Correlation of n-cirDNA, m-cirDNA, n-csbDNA, m-csbDNA, ACPA, CRP, and RF between each other and with...