Additional file 1: Figure S1. of A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis

Kyoko Honne (2657896)
Ingileif Hallgrímsdóttir (3445364)
Chunsen Wu (478983)
Ronnie Sebro (3445367)
Nicholas Jewell (763168)
Takeo Sakurai (807214)
Masahiro Iwamoto (466859)
Seiji Minota (2657893)
Damini Jawaheer (838750)

Publication date

January 2016

DOI

10.6084/m9.figshare.c.3607178_d2.v1

Abstract

Regional plots showing association results from GEE models at 6q15, 6q27 and 10q25.3, when the analyses were restricted to patients with moderate or severe disease activity at baseline (n = 413). (PDF 350 kb

Extracted data

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Additional file 1: Figure S1. of A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis

Kyoko Honne (2657896)
Ingileif Hallgrímsdóttir (3445364)
Chunsen Wu (478983)
Ronnie Sebro (3445367)
Nicholas Jewell (763168)
Takeo Sakurai (807214)
Masahiro Iwamoto (466859)
Seiji Minota (2657893)
Damini Jawaheer (838750)

Open link

Publication date

January 2016

DOI

10.6084/m9.figshare.c.3607178_d2.v1

Abstract

Extracted data

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Genes over-expressed in poor responders to therapy at baseline. Lists of probe sets differentially e...

Additional file 1: of Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation

Symen Ligthart (701678)
Ahmad Vaez (3165495)
Yi-Hsiang Hsu (247531)
Ronald Stolk (3399488)
AndrĂŠ Uitterlinden (3404267)
Albert Hofman (107303)
Behrooz Alizadeh (3503549)
Oscar Franco (2885594)
Abbas Dehghan (174878)

June 2016

Study-specific Methods Section for the Replication Section. Table S1. Replication Results for C-Reac...

Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis.

Martin, J.E.
Alizadeh, B.Z.
Gonzalez-Gay, M.A.
Balsa, A.
Pascual-Salcedo, D.
Fernandez-Gutierrez, B.
Raya, E.
Franke, L.
Slot, R. van 't
Coenen, M.J.H.
Riel, P.L.C.M. van
Radstake, T.R.D.J.
Koeleman, B.P.

January 2010

Contains fulltext : 88210.pdf (publisher's version ) (Closed access)OBJECTIVE: Gen...

Additional file 2: Figure S2. of A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis

Kyoko Honne (2657896)
Ingileif Hallgrímsdóttir (3445364)
Chunsen Wu (478983)
Ronnie Sebro (3445367)
Nicholas Jewell (763168)
Takeo Sakurai (807214)
Masahiro Iwamoto (466859)
Seiji Minota (2657893)
Damini Jawaheer (838750)

January 2016

Regions showing moderate evidence of association (p < 1x10−5) with anti-TNF response (GEE models). (...

Additional file 3: of Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Numbers of probe sets displaying a positive correlation with global disease activity indices and eac...

Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.

Liu, C.
Batliwalla, F.
Li, W.
Lee, A.
Roubenoff, R.
Beckman, E.
Khalili, H.
Damle, A.
Kern, M.
Furie, R.
Dupuis, J.
Plenge, R.M.
Coenen, M.J.H.
Behrens, T.W.
Carulli, J.P.
Gregersen, P.K.

January 2008

Contains fulltext : 70190.pdf (publisher's version ) (Open Access)The prediction o...

Additional file 1: Table S1. of Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

Klementy Shchetynsky (3710995)
Lina-Marcella Diaz-Gallo (3710998)
Lasse Folkersen (109487)
Aase Hensvold (3505412)
Anca Catrina (246690)
Louise Berg (54461)
Lars Klareskog (4149)
Leonid Padyukov (39206)

February 2017

Clinical features of studied groups of patients with RA and healthy controls. Table S2 The expressio...

Additional file 1: of Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis

Szilárd Póliska (3165450)
Timea Besenyei (6590546)
Edit Végh (6590549)
Attila Hamar (6590552)
Anita Pusztai (6590555)
Andrea Váncsa (6590558)
Nóra Bodnár (6590561)
Szilvia Szamosi (4799160)
Mária Csumita (6590564)
György Kerekes (6590570)
Zoltán Szabó (211818)
Zoltán Nagy (2668840)
Gabriella Szűcs (6590573)
Sándor Szántó (38675)
Gábor Zahuczky (215986)
László Nagy (2717482)
Zoltán Szekanecz (38677)

April 2019

Table S1. Association of gene expression profiles with vascular pathophysiology in biologic-naïve RA...

Additional file 8: Table S8. of A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy â results from a Swedish cohort study

Xia Jiang (210366)
Johan Askling (395864)
Saedis Saevarsdottir (395862)
Leonid Padyukov (39206)
Lars Alfredsson (39207)
Sebastien Viatte (433956)
Thomas Frisell (314752)

December 2016

Presenting associations between each of the 76 SNPs and EULAR response. (DOCX 37 kb

Additional file 14: Table S13. of A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy â results from a Swedish cohort study

Xia Jiang (210366)
Johan Askling (395864)
Saedis Saevarsdottir (395862)
Leonid Padyukov (39206)
Lars Alfredsson (39207)
Sebastien Viatte (433956)
Thomas Frisell (314752)

December 2016

Presenting associations between GRS SNPs and baseline clinical characteristics. (DOCX 18 kb

Additional file 11: Table S10. of A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy – results from a Swedish cohort study

Xia Jiang (210366)
Johan Askling (395864)
Saedis Saevarsdottir (395862)
Leonid Padyukov (39206)
Lars Alfredsson (39207)
Sebastien Viatte (433956)
Thomas Frisell (314752)

December 2016

Presenting associations between amino acid haplotypes and EULAR response, among patients with DAS28 ...

Additional file 1: of Identification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study

Seiji Nakamura (126240)
Katsuya Suzuki (1786093)
Hiroshi Iijima (3399872)
Yuko Hata (428188)
Chun Lim (3399875)
Yohei Ishizawa (3399869)
Hideto Kameda (3399878)
Koichi Amano (2543410)
Kenichi Matsubara (22850)
Ryo Matoba (1609)
Tsutomu Takeuchi (163145)

July 2016

Illustration of the distribution of patients in this observational study. (PDF 223 kb

Additional file 1: of Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Patients’ characteristics (immunohistochemistry studies on needle arthroscopic biopsies). Characteri...

Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis

Umicevic-Mirkov, M.
Cui, J.
Vermeulen, S.
Stahl, E.A.
Toonen, E.J.M.
Makkinje, R.R.
Lee, A.T.
Huizinga, T.W.J.
Allaart, R.
Barton, A.
Mariette, X.
Miceli, C.R.
Criswell, L.A.
Tak, P.P.
Vries, N de
Saevarsdottir, S.
Padyukov, L.
Bridges Jr, S.L.
Schaardenburg, D.J. van
Jansen, T.L.Th.A.
Dutmer, E.A.
Laar, M.A. van der
Barrera, P.
Radstake, T.R.D.J.
Riel, P.L.C.M. van
Scheffer, H.
Franke, B.
Brunner, H.G.
Plenge, R.M.
Gregersen, P.K.
Guchelaar (LUMC), H.J.
Coenen, M.J.H.

January 2013

BACKGROUND: Treatment strategies blocking tumour necrosis factor (anti-TNF) have proven very success...

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Genes over-expressed in poor responders to therapy at baseline. Lists of probe sets differentially e...

Additional file 1: of Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation

Symen Ligthart (701678)
Ahmad Vaez (3165495)
Yi-Hsiang Hsu (247531)
Ronald Stolk (3399488)
AndrĂŠ Uitterlinden (3404267)
Albert Hofman (107303)
Behrooz Alizadeh (3503549)
Oscar Franco (2885594)
Abbas Dehghan (174878)

June 2016

Study-specific Methods Section for the Replication Section. Table S1. Replication Results for C-Reac...

Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis.

Martin, J.E.
Alizadeh, B.Z.
Gonzalez-Gay, M.A.
Balsa, A.
Pascual-Salcedo, D.
Fernandez-Gutierrez, B.
Raya, E.
Franke, L.
Slot, R. van 't
Coenen, M.J.H.
Riel, P.L.C.M. van
Radstake, T.R.D.J.
Koeleman, B.P.

January 2010

Contains fulltext : 88210.pdf (publisher's version ) (Closed access)OBJECTIVE: Gen...

Additional file 2: Figure S2. of A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis

Kyoko Honne (2657896)
Ingileif Hallgrímsdóttir (3445364)
Chunsen Wu (478983)
Ronnie Sebro (3445367)
Nicholas Jewell (763168)
Takeo Sakurai (807214)
Masahiro Iwamoto (466859)
Seiji Minota (2657893)
Damini Jawaheer (838750)

January 2016

Regions showing moderate evidence of association (p < 1x10−5) with anti-TNF response (GEE models). (...

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Numbers of probe sets displaying a positive correlation with global disease activity indices and eac...

Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.

Liu, C.
Batliwalla, F.
Li, W.
Lee, A.
Roubenoff, R.
Beckman, E.
Khalili, H.
Damle, A.
Kern, M.
Furie, R.
Dupuis, J.
Plenge, R.M.
Coenen, M.J.H.
Behrens, T.W.
Carulli, J.P.
Gregersen, P.K.

January 2008

Contains fulltext : 70190.pdf (publisher's version ) (Open Access)The prediction o...

Additional file 1: Table S1. of Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

Klementy Shchetynsky (3710995)
Lina-Marcella Diaz-Gallo (3710998)
Lasse Folkersen (109487)
Aase Hensvold (3505412)
Anca Catrina (246690)
Louise Berg (54461)
Lars Klareskog (4149)
Leonid Padyukov (39206)

February 2017

Clinical features of studied groups of patients with RA and healthy controls. Table S2 The expressio...

Additional file 1: of Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis

Szilárd Póliska (3165450)
Timea Besenyei (6590546)
Edit Végh (6590549)
Attila Hamar (6590552)
Anita Pusztai (6590555)
Andrea Váncsa (6590558)
Nóra Bodnár (6590561)
Szilvia Szamosi (4799160)
Mária Csumita (6590564)
György Kerekes (6590570)
Zoltán Szabó (211818)
Zoltán Nagy (2668840)
Gabriella Szűcs (6590573)
Sándor Szántó (38675)
Gábor Zahuczky (215986)
László Nagy (2717482)
Zoltán Szekanecz (38677)

April 2019

Table S1. Association of gene expression profiles with vascular pathophysiology in biologic-naïve RA...

Additional file 8: Table S8. of A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy â results from a Swedish cohort study

Xia Jiang (210366)
Johan Askling (395864)
Saedis Saevarsdottir (395862)
Leonid Padyukov (39206)
Lars Alfredsson (39207)
Sebastien Viatte (433956)
Thomas Frisell (314752)

December 2016

Presenting associations between each of the 76 SNPs and EULAR response. (DOCX 37 kb

Additional file 14: Table S13. of A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy â results from a Swedish cohort study

Xia Jiang (210366)
Johan Askling (395864)
Saedis Saevarsdottir (395862)
Leonid Padyukov (39206)
Lars Alfredsson (39207)
Sebastien Viatte (433956)
Thomas Frisell (314752)

December 2016

Presenting associations between GRS SNPs and baseline clinical characteristics. (DOCX 18 kb

Additional file 11: Table S10. of A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy – results from a Swedish cohort study

Xia Jiang (210366)
Johan Askling (395864)
Saedis Saevarsdottir (395862)
Leonid Padyukov (39206)
Lars Alfredsson (39207)
Sebastien Viatte (433956)
Thomas Frisell (314752)

December 2016

Presenting associations between amino acid haplotypes and EULAR response, among patients with DAS28 ...

Additional file 1: of Identification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study

Seiji Nakamura (126240)
Katsuya Suzuki (1786093)
Hiroshi Iijima (3399872)
Yuko Hata (428188)
Chun Lim (3399875)
Yohei Ishizawa (3399869)
Hideto Kameda (3399878)
Koichi Amano (2543410)
Kenichi Matsubara (22850)
Ryo Matoba (1609)
Tsutomu Takeuchi (163145)

July 2016

Illustration of the distribution of patients in this observational study. (PDF 223 kb

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Patients’ characteristics (immunohistochemistry studies on needle arthroscopic biopsies). Characteri...

Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis

Umicevic-Mirkov, M.
Cui, J.
Vermeulen, S.
Stahl, E.A.
Toonen, E.J.M.
Makkinje, R.R.
Lee, A.T.
Huizinga, T.W.J.
Allaart, R.
Barton, A.
Mariette, X.
Miceli, C.R.
Criswell, L.A.
Tak, P.P.
Vries, N de
Saevarsdottir, S.
Padyukov, L.
Bridges Jr, S.L.
Schaardenburg, D.J. van
Jansen, T.L.Th.A.
Dutmer, E.A.
Laar, M.A. van der
Barrera, P.
Radstake, T.R.D.J.
Riel, P.L.C.M. van
Scheffer, H.
Franke, B.
Brunner, H.G.
Plenge, R.M.
Gregersen, P.K.
Guchelaar (LUMC), H.J.
Coenen, M.J.H.

January 2013

BACKGROUND: Treatment strategies blocking tumour necrosis factor (anti-TNF) have proven very success...

Aurélie De Groof (3581453)
Julie Ducreux (732980)
Frances Humby (84694)
Adrien Nzeusseu Toukap (732984)
Valérie Badot (3581456)
Costantino Pitzalis (23531)
Frédéric Houssiau (3581450)
Patrick Durez (11540)
Bernard Lauwerys (3462587)

January 2016

Genes over-expressed in poor responders to therapy at baseline. Lists of probe sets differentially e...

Additional file 1: of Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation

Symen Ligthart (701678)
Ahmad Vaez (3165495)
Yi-Hsiang Hsu (247531)
Ronald Stolk (3399488)
AndrĂŠ Uitterlinden (3404267)
Albert Hofman (107303)
Behrooz Alizadeh (3503549)
Oscar Franco (2885594)
Abbas Dehghan (174878)

June 2016

Study-specific Methods Section for the Replication Section. Table S1. Replication Results for C-Reac...

Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis.

Martin, J.E.
Alizadeh, B.Z.
Gonzalez-Gay, M.A.
Balsa, A.
Pascual-Salcedo, D.
Fernandez-Gutierrez, B.
Raya, E.
Franke, L.
Slot, R. van 't
Coenen, M.J.H.
Riel, P.L.C.M. van
Radstake, T.R.D.J.
Koeleman, B.P.

January 2010

Contains fulltext : 88210.pdf (publisher's version ) (Closed access)OBJECTIVE: Gen...

Additional file 1: Figure S1. of A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis

Abstract

Extracted data

Additional file 1: Figure S1. of A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis

Abstract

Extracted data

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