QC measures improve the power to detect biologically relevant allelic expression at genes that have eQTLs (eGenes), where individuals that are heterozygous for the top eQTL SNP (eSNP) are expected to have more allelic expression than homozygous individuals (extended). a QC measures increase the significance of the difference between heterozygous and homozygous individuals within eGenes. b QC measures reduce the variance of allelic expression between individuals within eGenes. (TIFF 2856Â kb
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Additional file 9: Figure S1. Algorithm verification using out-of-sample testing. (A) Percentage of ...
Full list of author information is available at the end of the articleBackground Genome-wide genetic...
QC measures reduce overdispersion in technical replicates when testing for allelic imbalance using a...
Quality control of genotype data for allelic expression analysis (extended). a Boxplot of per indivi...
Allelic expression signal from a population of monoclonal versus polyclonal cells. In the latter, st...
Genomic coverage of allelic expression data in Geuvadis CEU samples (extended). a Total number of un...
Summary of QC problems for AE data, proposed solutions, and potential drawbacks. (XLSX 31Â kb
Comparison of AE data generated with different alignment strategies. a–d For each comparison the obs...
Low-level reference bias at het-SNPs remains after filtering biased sites. a Boxplot of reference ra...
Model derivation: a derivation of the âinteraction modelâ used to find cancer eQTLs. (PDF 110 kb
<div><p>Studies of expression quantitative trait loci (eQTLs) offer insight into the molecular mecha...
This dataset is part of the manuscript: "Atlas of genetic effects in human microglia transcriptome a...
Effect of overlapping and duplicate reads on AE analysis of Geuvadis samples. a Histogram of percent...
Figure S1. a–c The distribution of Tajima’s D for DNase footprint SNPs in each subpopulation. d Over...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Additional file 9: Figure S1. Algorithm verification using out-of-sample testing. (A) Percentage of ...
Full list of author information is available at the end of the articleBackground Genome-wide genetic...
QC measures reduce overdispersion in technical replicates when testing for allelic imbalance using a...
Quality control of genotype data for allelic expression analysis (extended). a Boxplot of per indivi...
Allelic expression signal from a population of monoclonal versus polyclonal cells. In the latter, st...
Genomic coverage of allelic expression data in Geuvadis CEU samples (extended). a Total number of un...
Summary of QC problems for AE data, proposed solutions, and potential drawbacks. (XLSX 31Â kb
Comparison of AE data generated with different alignment strategies. a–d For each comparison the obs...
Low-level reference bias at het-SNPs remains after filtering biased sites. a Boxplot of reference ra...
Model derivation: a derivation of the âinteraction modelâ used to find cancer eQTLs. (PDF 110 kb
<div><p>Studies of expression quantitative trait loci (eQTLs) offer insight into the molecular mecha...
This dataset is part of the manuscript: "Atlas of genetic effects in human microglia transcriptome a...
Effect of overlapping and duplicate reads on AE analysis of Geuvadis samples. a Histogram of percent...
Figure S1. a–c The distribution of Tajima’s D for DNase footprint SNPs in each subpopulation. d Over...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Additional file 9: Figure S1. Algorithm verification using out-of-sample testing. (A) Percentage of ...
Full list of author information is available at the end of the articleBackground Genome-wide genetic...