oE2-specific ELISA antibody responses in mice after two subcutaneous immunisations.

<p>The individual response for each mouse is shown using a sera dilution of 1:1600. Group 1 (mouse 5 to 8) received 100 μg oE2 plus 10 μg Quil-A; Group 2 (mouse 5 to 8) received the FD 100 μg oE2 plus 10 μg Quil-A, Group 3 (mouse 5 to 8) received the oE2 nanovaccine (100 μg oE2 adsorbed to 500 μg SV-140), Group 4 (mouse 5 to 8) received the FD oE2 nanovaccine (100 μg oE2 adsorbed to 500 μg SV-140), Group 5 (mouse 5 to 8) received the FD 500 μg SV-140, Group 6 (mouse 5 to 8) was the unimmunised group and did not receive any vaccination. The letter ‘a’ denotes that the groups were not significantly different. Groups that do not share a common letter were significantly different (<i>p<</i>0.001, unpaired t-test analysis).