Evogliptin treatment reduced adipocyte size and distribution.

<p>HF-DIO mice were treated with exenatide (30 μg kg^-1, once daily, s.c.) or evogliptin at 0.027%, 0.081%, or 0.27% (w/w) for 2 weeks. The effects on adipocytes from epididymal fat tissues were histologically determined (three sections/animals, eight animals/group). (A) Representative images (original magnification, ×200), (B) mean adipocyte areas and (C-D) percentile distribution of adipocyte size were presented. #, <i>P</i> < 0.05 vs. lean control and *, <i>P</i> < 0.05 vs. HF-DIO control by one-way ANOVA.