Adipocyte size determination in mice with inactivated <i>Mest</i>.

<p>(A) A representative image shows variation in the size of adipocytes in eWAT of WT mice with high (WT-HM; n = 3) and low (WT-LM; n = 3) epididymal adipose tissue (eWAT) <i>Mest</i> expression and <i>Mest</i>^<b>pKO</b> (pKO) mice (n = 3). (B and C) Box and whisker graphs show the median and range of adipocyte sizes determined morphometrically for WT (n = 17), pKO (n = 10), WT-LM (n = 6) and WT-HM (n = 6) mice for both eWAT and inguinal adipose tissue (iWAT). Significance between groups was determined using two-tailed unpaired parametric t-tests. Datasets annotated with the same letter indicate no significant differences between groups.