<p>Effects of compounds MRTX, MRT94, MRT92, MRT83, MRTY and control compound in KU-812 cells on SMO RNA expression after 24h (a) or 72h (b) treatment at 10 μM and treatment after 24h (c) or 72h (d) at 50 μM. Data are expressed as the means ± SEM of three independent experiments performed in triplicate. *p<0.05 vs medium.</p
Three normal lung and 11 NSCLC cell lines were treated with different concentrations of PKM2 inhibit...
<p>RIN values calculated after pre-treatment (A) or co-treatment (B) of cells with SFN plus spermine...
<p>(A) NHBE cells were treated with 10 μM compound for 1 h or 3 μM compound for 24 h at 37°C and 5% ...
<p>Effects of compounds MRTX, MRT92 and control compound in K-562 cells (a-b) or KU-812 cells (c-d) ...
<p>Cells grown on 35-mm-diameter tissue culture dishes were overnight pretreated with CHL (10 nM) or...
<p>Effects of compounds MRTX (a), MRT94 (b), MRT92 (c) MRT83 (d), MRTY (e) and CUR61414 (f) (0.5–150...
<p>(A) Dose-response analysis of VPA treatment on cell proliferation of SMN-deficient NIH3T3-Smn<sub...
<p>(A) Analysis of cell proliferation in wild-type (Control), NIH3T3-Smn<sub>RNAi</sub>, NIH3T3-SMN2...
<p>(A) RT-qPCR analysis of mouse Smn mRNA levels in wild-type (Control), NIH3T3-Smn<sub>RNAi</sub>, ...
NSCLC cell lines were treated with different concentrations of SMI (10 to 80 μM). (A) number of viab...
<p>(A) S2 cells were transfected with Myc-Smo alone or in combination with HA-Hrs or Hrs dsRNA. Cell...
<p>Electropherograms of RNA size distribution recorded in untreated cultures and after 24 h of treat...
<p>(A) Cell extracts from S2 cells transfected with Myc-Smo, Myc-Smo<sup>K6R</sup>, Myc-Smo<sup>K7R<...
<p>(A) MCF-7 cells were treated with 10, 20, or 30 ng/mL PMA for 6 hr. Each bar represents the mean ...
<p>Effects of compounds MRTX, MRT94, MRT92, MRT83, MRTY and control compound after a 72h treatment a...
Three normal lung and 11 NSCLC cell lines were treated with different concentrations of PKM2 inhibit...
<p>RIN values calculated after pre-treatment (A) or co-treatment (B) of cells with SFN plus spermine...
<p>(A) NHBE cells were treated with 10 μM compound for 1 h or 3 μM compound for 24 h at 37°C and 5% ...
<p>Effects of compounds MRTX, MRT92 and control compound in K-562 cells (a-b) or KU-812 cells (c-d) ...
<p>Cells grown on 35-mm-diameter tissue culture dishes were overnight pretreated with CHL (10 nM) or...
<p>Effects of compounds MRTX (a), MRT94 (b), MRT92 (c) MRT83 (d), MRTY (e) and CUR61414 (f) (0.5–150...
<p>(A) Dose-response analysis of VPA treatment on cell proliferation of SMN-deficient NIH3T3-Smn<sub...
<p>(A) Analysis of cell proliferation in wild-type (Control), NIH3T3-Smn<sub>RNAi</sub>, NIH3T3-SMN2...
<p>(A) RT-qPCR analysis of mouse Smn mRNA levels in wild-type (Control), NIH3T3-Smn<sub>RNAi</sub>, ...
NSCLC cell lines were treated with different concentrations of SMI (10 to 80 μM). (A) number of viab...
<p>(A) S2 cells were transfected with Myc-Smo alone or in combination with HA-Hrs or Hrs dsRNA. Cell...
<p>Electropherograms of RNA size distribution recorded in untreated cultures and after 24 h of treat...
<p>(A) Cell extracts from S2 cells transfected with Myc-Smo, Myc-Smo<sup>K6R</sup>, Myc-Smo<sup>K7R<...
<p>(A) MCF-7 cells were treated with 10, 20, or 30 ng/mL PMA for 6 hr. Each bar represents the mean ...
<p>Effects of compounds MRTX, MRT94, MRT92, MRT83, MRTY and control compound after a 72h treatment a...
Three normal lung and 11 NSCLC cell lines were treated with different concentrations of PKM2 inhibit...
<p>RIN values calculated after pre-treatment (A) or co-treatment (B) of cells with SFN plus spermine...
<p>(A) NHBE cells were treated with 10 μM compound for 1 h or 3 μM compound for 24 h at 37°C and 5% ...