<p>Potencies against intracellular <i>T</i>. <i>cruzi</i> for control compounds (N = 3).</p
<p>a: <i>T</i>. <i>cruzi</i> CYP51 inhibition plotted against <i>T</i>. <i>cruzi</i> activity for co...
<p><i>In vitro</i> inhibitory effects of compounds 1a-2b against the proliferation of three human ca...
Parasite proliferation inhibition (PPI). The rows shaded in grey highlight the hit molecules.</p
<p><sup>a</sup><i>T</i>. <i>cruzi</i>, strain Tulahuen C4, intracellular amastigotes.</p><p><sup>b</...
<p><i>T. cruzi</i> intracellular multiplication was evaluated at 52 hr of incubation at several conc...
<p>The IC50 reported from the HTS available at Pubchem and the IC50 determined in our laboratory are...
<p>Infected LLCMK<sub>2</sub> cells were incubated in the presence of different concentrations of qu...
Naturally occurring cytochalasins A-D and their percentage inhibition in the screening against T. cr...
(a) Control for cell line H-157, (b) intracellular drug distribution (2mM drug) and drug-induced cel...
<p>Strains Silvio X10/7, Y and PAH1790 assessed after 5 days treatment with nifurtimox <b>(A)</b> be...
<p>IC50 and MIC50 against <i>M</i>. <i>mycetomatis</i> of the 13 most active compounds identified in...
Chagas disease is caused by infection with the protozoan parasite, Trypanosoma cruzi. The disease ca...
<p>Their host cell toxicity (TC<sub>50</sub>) and anti-<i>T. cruzi</i> (IC<sub>50</sub> for the ‘Am/...
The development of new drugs against Chagas disease is a priority since the currently available medi...
<p><i>In vitro</i> activities of drugs tested against <i>P</i>. <i>falciparum</i> 3D7 strain.</p
<p>a: <i>T</i>. <i>cruzi</i> CYP51 inhibition plotted against <i>T</i>. <i>cruzi</i> activity for co...
<p><i>In vitro</i> inhibitory effects of compounds 1a-2b against the proliferation of three human ca...
Parasite proliferation inhibition (PPI). The rows shaded in grey highlight the hit molecules.</p
<p><sup>a</sup><i>T</i>. <i>cruzi</i>, strain Tulahuen C4, intracellular amastigotes.</p><p><sup>b</...
<p><i>T. cruzi</i> intracellular multiplication was evaluated at 52 hr of incubation at several conc...
<p>The IC50 reported from the HTS available at Pubchem and the IC50 determined in our laboratory are...
<p>Infected LLCMK<sub>2</sub> cells were incubated in the presence of different concentrations of qu...
Naturally occurring cytochalasins A-D and their percentage inhibition in the screening against T. cr...
(a) Control for cell line H-157, (b) intracellular drug distribution (2mM drug) and drug-induced cel...
<p>Strains Silvio X10/7, Y and PAH1790 assessed after 5 days treatment with nifurtimox <b>(A)</b> be...
<p>IC50 and MIC50 against <i>M</i>. <i>mycetomatis</i> of the 13 most active compounds identified in...
Chagas disease is caused by infection with the protozoan parasite, Trypanosoma cruzi. The disease ca...
<p>Their host cell toxicity (TC<sub>50</sub>) and anti-<i>T. cruzi</i> (IC<sub>50</sub> for the ‘Am/...
The development of new drugs against Chagas disease is a priority since the currently available medi...
<p><i>In vitro</i> activities of drugs tested against <i>P</i>. <i>falciparum</i> 3D7 strain.</p
<p>a: <i>T</i>. <i>cruzi</i> CYP51 inhibition plotted against <i>T</i>. <i>cruzi</i> activity for co...
<p><i>In vitro</i> inhibitory effects of compounds 1a-2b against the proliferation of three human ca...
Parasite proliferation inhibition (PPI). The rows shaded in grey highlight the hit molecules.</p
DOI
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