<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Parameters <i>z</i><sub><i>0</i></sub>, <i>η</i><sub><i>1</i>,</sub> <i>η</i><sub><i>2</i></sub>, <i>IP</i> and <i>SF</i> fitted as patient specific, other parameters fitted per group. Mauve, grey and blue curves show 100 samples from the posterior distributions of antibody, virus and target cell trajectories, respectively. Median fits are shown as bold lines (purple shows IgM, black shows virus). Parameter estimates are shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004951#pcbi.1004951.t002" target="_blank">Table 2</a>. Subjects classified as primary infections highlighted with green outline.</p
A: Ex vivo ELISpot responses to DENV NS1, NS3, NS5 and combined DENV-ALL overlapping peptides in pat...
<p>(A) O-PLS scatter plot showing how the patients (n = 42) separate in a model based on 139 paramet...
<p><b>A.</b> Percentage of PB/PCs circulating in the blood of patients suspected of DENV infection. ...
<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Param...
<p>Fit of the model to virus and IgM measurements for DENV1-infected subjects for the ADCC model var...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
<p>The left hand axis shows log<sub>10</sub> RNA copies/ml of plasma in black. The right hand axis s...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
Violin plots show the shape of the distribution of VES,Cox estimates. The colored solid lines show t...
(A) Age distributions of the reported case numbers during the epidemic periods (red, blue, green, ye...
<p>(A) Representative histogram plots showing expression of the potential maturation markers on pDCs...
Model fits for the measurements observed using the DENV-2/16681 strain with no medium refresh and an...
<p>Sera collected from three DENV1 vaccine recipients at five times post-vaccination were tested for...
<p><b>A.</b> IgG serum avidity to DENV3 day 14–28 (convalescent), 3 m, 6 m and 18 m post-onset of sy...
A: Ex vivo ELISpot responses to DENV NS1, NS3, NS5 and combined DENV-ALL overlapping peptides in pat...
<p>(A) O-PLS scatter plot showing how the patients (n = 42) separate in a model based on 139 paramet...
<p><b>A.</b> Percentage of PB/PCs circulating in the blood of patients suspected of DENV infection. ...
<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Param...
<p>Fit of the model to virus and IgM measurements for DENV1-infected subjects for the ADCC model var...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
<p>The left hand axis shows log<sub>10</sub> RNA copies/ml of plasma in black. The right hand axis s...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
Violin plots show the shape of the distribution of VES,Cox estimates. The colored solid lines show t...
(A) Age distributions of the reported case numbers during the epidemic periods (red, blue, green, ye...
<p>(A) Representative histogram plots showing expression of the potential maturation markers on pDCs...
Model fits for the measurements observed using the DENV-2/16681 strain with no medium refresh and an...
<p>Sera collected from three DENV1 vaccine recipients at five times post-vaccination were tested for...
<p><b>A.</b> IgG serum avidity to DENV3 day 14–28 (convalescent), 3 m, 6 m and 18 m post-onset of sy...
A: Ex vivo ELISpot responses to DENV NS1, NS3, NS5 and combined DENV-ALL overlapping peptides in pat...
<p>(A) O-PLS scatter plot showing how the patients (n = 42) separate in a model based on 139 paramet...
<p><b>A.</b> Percentage of PB/PCs circulating in the blood of patients suspected of DENV infection. ...