<p>Fit of the model to virus and IgM measurements for DENV1-infected subjects for the ADCC model variant. Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Parameters <i>z</i><sub><i>0</i></sub>, <i>η</i><sub><i>1</i>,</sub> <i>η</i><sub><i>2</i></sub>, <i>IP</i> and <i>SF</i> fitted as patient specific, other parameters fitted per group. Mauve, grey and blue curves show 100 samples from the posterior distributions of antibody, virus and target cell trajectories, respectively. Median fits are shown as bold lines (purple shows IgM, black shows virus). Parameter estimates are shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004951#pcbi.1004951.t003" target="_blank">...
Violin plots show the shape of the distribution of VES,Cox estimates. The colored solid lines show t...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
<p>Demographics and clinical parameters of patients infected with DENV with different serotypes.</p
<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Param...
<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Param...
<p>The left hand axis shows log<sub>10</sub> RNA copies/ml of plasma in black. The right hand axis s...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
<p><b>A.</b> Percentage of PB/PCs circulating in the blood of patients suspected of DENV infection. ...
<p>(A) Representative histogram plots showing expression of the potential maturation markers on pDCs...
<p>The mean of relative proportion (%) of mDCs, pDCs, and DN were analyzed in blood samples from 68 ...
A: Ex vivo ELISpot responses to DENV NS1, NS3, NS5 and combined DENV-ALL overlapping peptides in pat...
<p>(A) Representative histogram plots showing maturation markers on mDCs on blood samples from healt...
<p>Distribution of each of the three mDC subsets as a percentage of total DCs during acute DENV was ...
<p><b>A.</b> IgG serum avidity to DENV3 day 14–28 (convalescent), 3 m, 6 m and 18 m post-onset of sy...
Violin plots show the shape of the distribution of VES,Cox estimates. The colored solid lines show t...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
<p>Demographics and clinical parameters of patients infected with DENV with different serotypes.</p
<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Param...
<p>Each plot shows an individual patient. Virus data is shown in black and IgM data in purple. Param...
<p>The left hand axis shows log<sub>10</sub> RNA copies/ml of plasma in black. The right hand axis s...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
<p><b>A.</b> Percentage of PB/PCs circulating in the blood of patients suspected of DENV infection. ...
<p>(A) Representative histogram plots showing expression of the potential maturation markers on pDCs...
<p>The mean of relative proportion (%) of mDCs, pDCs, and DN were analyzed in blood samples from 68 ...
A: Ex vivo ELISpot responses to DENV NS1, NS3, NS5 and combined DENV-ALL overlapping peptides in pat...
<p>(A) Representative histogram plots showing maturation markers on mDCs on blood samples from healt...
<p>Distribution of each of the three mDC subsets as a percentage of total DCs during acute DENV was ...
<p><b>A.</b> IgG serum avidity to DENV3 day 14–28 (convalescent), 3 m, 6 m and 18 m post-onset of sy...
Violin plots show the shape of the distribution of VES,Cox estimates. The colored solid lines show t...
Kinetics for 6 of the seven model compartments for the best fit model are plotted. Since infected ce...
<p>Demographics and clinical parameters of patients infected with DENV with different serotypes.</p