The percentage of different mutational subtypes across all defined hotspot mutations. On each hotspot locus, only the mutational subtype that occupies the highest number of mutations was counted. (PDF 85 kb
Figure S3. DNA copy number alterations in the IBC cohort. The genes with DNA copy number alterations...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
Figure S4. Oncoprint showing a subset of mutations in OV. Line plots above the oncoprint shows the t...
Twenty mutation subtypes that were included in the statistical modeling of hotspot mutation definiti...
Relative frequencies of non-coding mutation contexts in different cancer types. (top panel) Three ca...
Figure S5. Connectivity in the map between the 25 most frequently mutated genes and hallmarks. Simil...
Figure S2. Hotspot mutation and CCF. (a) Maximum value of CCF in COADREAD. Each dot means a tumor pa...
Figure S3. Connectivity in the map between genes and hallmarks. The heatmap indicates the membership...
Figure S3. Correlation between variant allele frequencies detected by Cancer Hotspot Panel V2 and Ma...
<p>A. shows the distribution of mutational hotspots for different cancer types within a given domain...
The relationship between the number of potential sites for a given type of mutations and the number ...
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Log10 of total mutations per genome, ordered by median mutations within each tumour type. Figure S2:...
a Mutational signatures for each sample in the discovery set. b Mutational signatures found in the d...
Figure S4. Connectivity in the map between the 25 most frequently mutated genes and pathways. Simila...
Figure S3. DNA copy number alterations in the IBC cohort. The genes with DNA copy number alterations...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
Figure S4. Oncoprint showing a subset of mutations in OV. Line plots above the oncoprint shows the t...
Twenty mutation subtypes that were included in the statistical modeling of hotspot mutation definiti...
Relative frequencies of non-coding mutation contexts in different cancer types. (top panel) Three ca...
Figure S5. Connectivity in the map between the 25 most frequently mutated genes and hallmarks. Simil...
Figure S2. Hotspot mutation and CCF. (a) Maximum value of CCF in COADREAD. Each dot means a tumor pa...
Figure S3. Connectivity in the map between genes and hallmarks. The heatmap indicates the membership...
Figure S3. Correlation between variant allele frequencies detected by Cancer Hotspot Panel V2 and Ma...
<p>A. shows the distribution of mutational hotspots for different cancer types within a given domain...
The relationship between the number of potential sites for a given type of mutations and the number ...
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Log10 of total mutations per genome, ordered by median mutations within each tumour type. Figure S2:...
a Mutational signatures for each sample in the discovery set. b Mutational signatures found in the d...
Figure S4. Connectivity in the map between the 25 most frequently mutated genes and pathways. Simila...
Figure S3. DNA copy number alterations in the IBC cohort. The genes with DNA copy number alterations...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
Figure S4. Oncoprint showing a subset of mutations in OV. Line plots above the oncoprint shows the t...