Twenty mutation subtypes that were included in the statistical modeling of hotspot mutation definition. (PDF 34 kb
Figure S2. Distribution of genes with novel mutations based on individual patients. (A) Distribution...
Table S1. Significant mutually exclusive (ME) and co-occurring (CO) associations across all cancer t...
The relationship between the number of potential sites for a given type of mutations and the number ...
The percentage of different mutational subtypes across all defined hotspot mutations. On each hotspo...
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Clinical and treatment characteristics of the 18 cases with no ctDNA alterations detected. Table S2....
Figure S2. Hotspot mutation and CCF. (a) Maximum value of CCF in COADREAD. Each dot means a tumor pa...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
Log10 of total mutations per genome, ordered by median mutations within each tumour type. Figure S2:...
Relative frequencies of non-coding mutation contexts in different cancer types. (top panel) Three ca...
Supplementary methods and results. This document contains supplementary text about the multilevel ma...
Figure S3. Correlation between variant allele frequencies detected by Cancer Hotspot Panel V2 and Ma...
Table S2. Pathogenic and likely pathogenic mutations identified in the studied cohort. Annotations a...
Table S1. Clinical characteristics of the enrolled 32 NSCLC patients. Table S2. List of target regio...
Table S9. Comparison of the results obtained by using different cutoffs to define the higher-TMB and...
Figure S2. Distribution of genes with novel mutations based on individual patients. (A) Distribution...
Table S1. Significant mutually exclusive (ME) and co-occurring (CO) associations across all cancer t...
The relationship between the number of potential sites for a given type of mutations and the number ...
The percentage of different mutational subtypes across all defined hotspot mutations. On each hotspo...
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Clinical and treatment characteristics of the 18 cases with no ctDNA alterations detected. Table S2....
Figure S2. Hotspot mutation and CCF. (a) Maximum value of CCF in COADREAD. Each dot means a tumor pa...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
Log10 of total mutations per genome, ordered by median mutations within each tumour type. Figure S2:...
Relative frequencies of non-coding mutation contexts in different cancer types. (top panel) Three ca...
Supplementary methods and results. This document contains supplementary text about the multilevel ma...
Figure S3. Correlation between variant allele frequencies detected by Cancer Hotspot Panel V2 and Ma...
Table S2. Pathogenic and likely pathogenic mutations identified in the studied cohort. Annotations a...
Table S1. Clinical characteristics of the enrolled 32 NSCLC patients. Table S2. List of target regio...
Table S9. Comparison of the results obtained by using different cutoffs to define the higher-TMB and...
Figure S2. Distribution of genes with novel mutations based on individual patients. (A) Distribution...
Table S1. Significant mutually exclusive (ME) and co-occurring (CO) associations across all cancer t...
The relationship between the number of potential sites for a given type of mutations and the number ...
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