c-Fos bound proximal regions are depleted of AP-1 motifs.

<p>Proportion of AP-1 motif occurrence in proximal and distal genomic ChIP-seq intervals bound by c-Fos, but not by NF-YB are shown. Proximal (p) and distal (d) genomic intervals targeted by c-Fos, but not by NF-YB (column c-Fos of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0160803#pone.0160803.t001" target="_blank">Table 1</a>) differ significantly in the occurrence of AP-1 motifs detected by an AP-1 PWM (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0160803#pone.0160803.g001" target="_blank">Fig 1</a>); AP-1+: number of intervals with, AP-1−: without a detectable AP-1 motif. In the last column the Fisher’s Exact Odds Ratios (OR, bold) and the corresponding P-values (in parentheses) are given.