<p>We used cell type specific chromatin state data (Broad ChromHMM) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0160803#pone.0160803.ref023" target="_blank">23</a>] to identify the proportion of the high-scoring AP-1 motif containing distal genomic intervals that overlap with ENCODE defined enhancers. We analyzed the overlaps for the HUVEC, K562, and GM12878 cell lines (rows) and relate them to the AP-1+ motif containing genomic intervals.</p
A problem of substantial interest is to systematically map variation in chromatin structure to gene...
Chromatin state variation at gene regulatory elements is abundant across individuals, yet we underst...
<p>Normalized ATAC-seq signal of anterior (orange), posterior (blue), whole embryo (gray) is depicte...
<p>The percentage of genomic intervals that harbor an AP-1 motif was calculated and plotted against ...
<p>Proportion of AP-1 motif occurrence in proximal and distal genomic ChIP-seq intervals bound by c-...
<p>In contrast to the proximal genomic intervals no enrichment of CCAAT box motifs was found in the ...
Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory...
Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory...
<p>MRT profile along two Mb long fragments of human chromosome 5 (left) and 14 (right). U-domains ar...
<p>Origins associated with a given chromatin state (in percent) correspond to origins that overlap w...
SummaryDeciphering the impact of genetic variants on gene regulation is fundamental to understanding...
A problem of substantial interest is to systematically map variation in chromatin structure to gene ...
<p>(A) Distribution of p53 ChIP-seq peaks among chromatin states (ChromHMM7) and the median distance...
<p>(A) Ratio of the observed fraction of overlapping fragments to the expected one. Observed fractio...
Chromatin state variation at gene regulatory elements is abundant across individuals, yet we underst...
A problem of substantial interest is to systematically map variation in chromatin structure to gene...
Chromatin state variation at gene regulatory elements is abundant across individuals, yet we underst...
<p>Normalized ATAC-seq signal of anterior (orange), posterior (blue), whole embryo (gray) is depicte...
<p>The percentage of genomic intervals that harbor an AP-1 motif was calculated and plotted against ...
<p>Proportion of AP-1 motif occurrence in proximal and distal genomic ChIP-seq intervals bound by c-...
<p>In contrast to the proximal genomic intervals no enrichment of CCAAT box motifs was found in the ...
Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory...
Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory...
<p>MRT profile along two Mb long fragments of human chromosome 5 (left) and 14 (right). U-domains ar...
<p>Origins associated with a given chromatin state (in percent) correspond to origins that overlap w...
SummaryDeciphering the impact of genetic variants on gene regulation is fundamental to understanding...
A problem of substantial interest is to systematically map variation in chromatin structure to gene ...
<p>(A) Distribution of p53 ChIP-seq peaks among chromatin states (ChromHMM7) and the median distance...
<p>(A) Ratio of the observed fraction of overlapping fragments to the expected one. Observed fractio...
Chromatin state variation at gene regulatory elements is abundant across individuals, yet we underst...
A problem of substantial interest is to systematically map variation in chromatin structure to gene...
Chromatin state variation at gene regulatory elements is abundant across individuals, yet we underst...
<p>Normalized ATAC-seq signal of anterior (orange), posterior (blue), whole embryo (gray) is depicte...