Additional file 15 of Proteobacteria explain significant functional variability in the human gut microbiome

Figure S13. Genes only annotated in Proteobacteria or Euryarchaeota, but not Actinobacteria or Firmicutes, are more likely to be variable. (A) Bar plots give the fraction of gene families with at least one bacterial or archaeal representative in each category (significantly invariable, non-significant, and significantly variable) that were annotated onlyin the phylum listed (x-axis). Significance was assessed as in Additional file 13: Figure S12, using a Holm correction for significance. p values are color-coded by whether a phylum was enriched (red), depleted (blue), or neither (gray) for variable gene families (Holm-corrected p≤0.1). (B) Bar plots are as per (A), but test results come from a test sampling equal parts phylum-specific genes and genes annotated in all four listed phyla, with phylum-specific genes themselves uniformly sampled across phyla. (PDF 149 kb