Additional file 4 of Proteobacteria explain significant functional variability in the human gut microbiome

Figure S4. Size parameter estimation affects power and α, with the mode method-of-moments giving the best control. α (A) was minimized and power (B) was maximized when the mode method-of-moments estimator was used to get estimates of the study-specific dispersion parameters k y ̂ $\widehat {k_{y}}$ . Bars are from four simulations. The proportion of variable/invariable gene families was 0.4, and 43% of genes were true positives. (PDF 44 kb