Intracellular TFV-DP concentrations in vaginal tissues and inguinal and iliac lymph nodes collected at necropsy.

<p>Blue, Day 34 (<i>N</i> = 2); red, Day 35 (<i>N</i> = 2); and green, Day 36 (<i>N</i> = 2). The intracellular TFV-DP levels are maintained 4–6 days after pod-IVR removal on Day 30. The box plots represent the analytical lower limits of quantitation (LLOQ) associated with the TFV-DP measurements, where the box extends from the 25th to 75th percentiles, with the horizontal line in the box representing the median; whiskers represent the lowest and highest datum. The assay has an LLOQ of 50 fmol per sample, which is divided by the number of cells collected in each sample to afford the individual LLOQs represented here.