Blood CD4⁺ T cells and endometrial epithelial cells and fibroblasts metabolize TFV to TFV-DP.

<p>TFV-DP levels were measured by LC-MS/MS in increasing numbers of purified blood CD4⁺ T cells (A and B) and EM epithelial cells (C) and fibroblasts (D) treated with indicated dose of TFV for 24 hr. Bars represent mean and SEM from triplicate cultures. Values are expressed as fmol per ml in (A) and fmol/million cells in (B, C and D).