Mucosal concentrations of TFV and TFV-DP based on community state type (CST) at end of treatment (visit 7) for TFV and TFV/LNG IVR users combined.</p
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
<p>TFV-DP levels were measured by LC-MS/MS in purified cultures of epithelial cells (n = 14), fibrob...
<p>TFV-DP levels were measured by LC-MS/MS in purified cultures of EM (n = 4), CX (n = 7) and ECX (n...
Community state type (CST) frequencies at visit 7 for TFV, TFV/LNG and Placebo IVR users combining a...
<p>Intracellular TFV-DP and FTC-TP concentrations at 24 h and 3 days in vaginal, rectal, and lymphoi...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
<p>Intracellular TFVdp concentration in isolated rectal mucosal mononuclear cells increases linearly...
<p>Data from end-of-period visit showing median (interquartile range) by dosing regimen in common co...
A. TFV concentrations in the CV aspirate among active IVR users with Lactobacillus dominated (LB) CS...
<p>Each set of figures documents the 30 min drug quantification in the left-side graph and the 24 hr...
<p>The solid blue-, dash-dotted green, dashed red and dotted black lines show the concentration-resp...
<p>Blue, Day 34 (<i>N</i> = 2); red, Day 35 (<i>N</i> = 2); and green, Day 36 (<i>N</i> = 2). The in...
<p>A: Predicted intracellular pharmacokinetics of TFV-DP in PBMCs after a single 300 mg oral TDF dos...
<p>Side-by-side boxplots of end-of-period visit data for all participants by anatomic site and dosin...
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
<p>TFV-DP levels were measured by LC-MS/MS in purified cultures of epithelial cells (n = 14), fibrob...
<p>TFV-DP levels were measured by LC-MS/MS in purified cultures of EM (n = 4), CX (n = 7) and ECX (n...
Community state type (CST) frequencies at visit 7 for TFV, TFV/LNG and Placebo IVR users combining a...
<p>Intracellular TFV-DP and FTC-TP concentrations at 24 h and 3 days in vaginal, rectal, and lymphoi...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
<p>Intracellular TFVdp concentration in isolated rectal mucosal mononuclear cells increases linearly...
<p>Data from end-of-period visit showing median (interquartile range) by dosing regimen in common co...
A. TFV concentrations in the CV aspirate among active IVR users with Lactobacillus dominated (LB) CS...
<p>Each set of figures documents the 30 min drug quantification in the left-side graph and the 24 hr...
<p>The solid blue-, dash-dotted green, dashed red and dotted black lines show the concentration-resp...
<p>Blue, Day 34 (<i>N</i> = 2); red, Day 35 (<i>N</i> = 2); and green, Day 36 (<i>N</i> = 2). The in...
<p>A: Predicted intracellular pharmacokinetics of TFV-DP in PBMCs after a single 300 mg oral TDF dos...
<p>Side-by-side boxplots of end-of-period visit data for all participants by anatomic site and dosin...
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
<p>TFV-DP levels were measured by LC-MS/MS in purified cultures of epithelial cells (n = 14), fibrob...
<p>TFV-DP levels were measured by LC-MS/MS in purified cultures of EM (n = 4), CX (n = 7) and ECX (n...