TAGLN2 regulates mesenchymal markers in primary GBM cells. (A) Knocking down TAGLN2 in mesenchymal GBM#P3 cells significantly reduced the expression of mesenchymal markers including CD44, CHI3L1, N-cadherin and FoxM1. GAPDH was used as a loading control. (B and C) Neurosphere formation capacity of GBM#P3 cells decreased significantly after TAGLN2 knockdown (scale bar = 100 μm). Results are representative of three independent experiments. *P < 0.05. (TIFF 801 kb
Figure S1. TRIM14 is overexpression in GBM and correlates with poor prognosis. (A) The expression of...
Figure S4. Relative TNC expression differs across single-cell subpopulations. Single cell RNA-Seq of...
Figure S1. (A) U87 cells pretreated with a lentivirus with sh-miR155HG or sh-NC and a lentivirus con...
TAGLN2 enrichment in mesenchymal subtype gliomas. (A) GSEA analysis showed that mesenchymal-associat...
TAGLN2 expression pattern in different anatomical structures in GBM tissue. Representative images of...
Glial cells exposed to GBM CM do not change the expression of senescence-associated secretory phenot...
Figure S3. NAC causes G1 arrest in GBM cells. A, The cell cycle analysis by measuring the percentage...
Expression of the selected genes and proteins in the NAT12/NAA30 knockdown cultures. A, Western blot...
Figure S3. nuclear and cytosol proteins were isolated from LN229 cells. The expression levels of ITG...
Figure S2. TRIM14 promotes proliferation in glioma. (A) CCK-8 assay displays decreased proliferation...
The differential expressive genes between U87 and U251 glioma cell lines. (A) Heatmap showed the dif...
Figure S1. (A) ITGB4 mRNA expression in brain tissues (n = 23) and diffuse astrocytoma tissues (n = ...
Microarray analysis of the selected NAT genes. A, Expression of NAA30/NAT12 in tissues and cells. Ex...
Figure S2. The patient-derived GBM cells displayed a higher level of TGF-β1 and TGF-β2. A, Represent...
Figure S2. The effects of PBX3 overexpression or knockdown on glioma cell migration and invasion. (A...
Figure S1. TRIM14 is overexpression in GBM and correlates with poor prognosis. (A) The expression of...
Figure S4. Relative TNC expression differs across single-cell subpopulations. Single cell RNA-Seq of...
Figure S1. (A) U87 cells pretreated with a lentivirus with sh-miR155HG or sh-NC and a lentivirus con...
TAGLN2 enrichment in mesenchymal subtype gliomas. (A) GSEA analysis showed that mesenchymal-associat...
TAGLN2 expression pattern in different anatomical structures in GBM tissue. Representative images of...
Glial cells exposed to GBM CM do not change the expression of senescence-associated secretory phenot...
Figure S3. NAC causes G1 arrest in GBM cells. A, The cell cycle analysis by measuring the percentage...
Expression of the selected genes and proteins in the NAT12/NAA30 knockdown cultures. A, Western blot...
Figure S3. nuclear and cytosol proteins were isolated from LN229 cells. The expression levels of ITG...
Figure S2. TRIM14 promotes proliferation in glioma. (A) CCK-8 assay displays decreased proliferation...
The differential expressive genes between U87 and U251 glioma cell lines. (A) Heatmap showed the dif...
Figure S1. (A) ITGB4 mRNA expression in brain tissues (n = 23) and diffuse astrocytoma tissues (n = ...
Microarray analysis of the selected NAT genes. A, Expression of NAA30/NAT12 in tissues and cells. Ex...
Figure S2. The patient-derived GBM cells displayed a higher level of TGF-β1 and TGF-β2. A, Represent...
Figure S2. The effects of PBX3 overexpression or knockdown on glioma cell migration and invasion. (A...
Figure S1. TRIM14 is overexpression in GBM and correlates with poor prognosis. (A) The expression of...
Figure S4. Relative TNC expression differs across single-cell subpopulations. Single cell RNA-Seq of...
Figure S1. (A) U87 cells pretreated with a lentivirus with sh-miR155HG or sh-NC and a lentivirus con...