<p>A. Plasma cytokines were measured by multiplex ELISA. As indicated, plasma samples were collected at 20 days of age from F+/+ ND and DR+/+ ND rats and at 30 days of age in F+/+ ND, DR+/+ ND, DR+/+ HCD and DR+/+ B/S rats. The lowest reliable detection level (lowest standard) is shown with a dotted line. Significance based on rank-sum test: * p < 0.05, ** p < 0.01,***p < 0.001, † p < 0.0001 versus 20-day-old DR<i>+/+</i> rats. Error bars = SEM. B. Total TLR4 receptor activity induced by plasma collected at 30 and 60 days of age from F+/+ ND, DR+/+ ND, 30 days of age from DR+/+ HCD and DR+/+ B/S rats. * p < 0.05 when compared to day 30 DR +/+ ND. ** p < 0.05 when compared to day 60 DR+/+ ND. Error bars = SEM.</p
<p>Plasma biomarkers were measured by ELISA in the plasma of subjects ranging from 24–81 years of ag...
<p>(<b>A</b>) Western blot detection of the HSP70 and HMGB1 protein expression levels in various gro...
<p>Immunohistochemical analysis of TLR2 expression level in rat renal tissues in different age group...
<p>RD0-21 or HFD0-21: pooled data between days 0–21. Data are reported as mean ± S.D. and expressed ...
<p>All data were determined under fed conditions. Values (pg/ml) are mean ± SEM for the number (<i>n...
<p>Whole blood samples from neonate-infant subjects were followed longitudinally from 2 weeks (2 wk;...
<p>Compared with the 3-month-old group, the fold change in inflammatory cytokines in the 12-month-ol...
<p>Groups are as defined in figure legend 2. Data is shown for (A) TNF-alpha, (B) IL-6, (C) IL-10, (...
<p>DC were identified as in Figure 1. (A) Mean fluorescence intensity (MFI) of cell surface molecule...
<p>A–B; Agonist-induced production of IL-12p70 (A) and IL-10 (B) by adult PBMC stimulated in the pre...
<p>Whole blood samples from ∼30 neonate-infant subjects were followed longitudinally from 2 weeks (2...
<p>Cytokine and chemokine levels in serum from HIV-1Tg rats (red bars) and F344 age-matched control ...
<p>At day 90 post-immunization, plasma levels of IL-10 (A), IL-4 (B), MCP-1 (C) and OPG (D) did not ...
<p>IL-10 (A). IL-12 (B). IL-10/IL-12 ratio (C). IL-23 (D). Data are the mean ± SD. <i>n</i> = 7–8....
<p>Young BALB/c and B6 cDC and DCreg were stained for co-stimulatory (A) and inhibitory (B) cell sur...
<p>Plasma biomarkers were measured by ELISA in the plasma of subjects ranging from 24–81 years of ag...
<p>(<b>A</b>) Western blot detection of the HSP70 and HMGB1 protein expression levels in various gro...
<p>Immunohistochemical analysis of TLR2 expression level in rat renal tissues in different age group...
<p>RD0-21 or HFD0-21: pooled data between days 0–21. Data are reported as mean ± S.D. and expressed ...
<p>All data were determined under fed conditions. Values (pg/ml) are mean ± SEM for the number (<i>n...
<p>Whole blood samples from neonate-infant subjects were followed longitudinally from 2 weeks (2 wk;...
<p>Compared with the 3-month-old group, the fold change in inflammatory cytokines in the 12-month-ol...
<p>Groups are as defined in figure legend 2. Data is shown for (A) TNF-alpha, (B) IL-6, (C) IL-10, (...
<p>DC were identified as in Figure 1. (A) Mean fluorescence intensity (MFI) of cell surface molecule...
<p>A–B; Agonist-induced production of IL-12p70 (A) and IL-10 (B) by adult PBMC stimulated in the pre...
<p>Whole blood samples from ∼30 neonate-infant subjects were followed longitudinally from 2 weeks (2...
<p>Cytokine and chemokine levels in serum from HIV-1Tg rats (red bars) and F344 age-matched control ...
<p>At day 90 post-immunization, plasma levels of IL-10 (A), IL-4 (B), MCP-1 (C) and OPG (D) did not ...
<p>IL-10 (A). IL-12 (B). IL-10/IL-12 ratio (C). IL-23 (D). Data are the mean ± SD. <i>n</i> = 7–8....
<p>Young BALB/c and B6 cDC and DCreg were stained for co-stimulatory (A) and inhibitory (B) cell sur...
<p>Plasma biomarkers were measured by ELISA in the plasma of subjects ranging from 24–81 years of ag...
<p>(<b>A</b>) Western blot detection of the HSP70 and HMGB1 protein expression levels in various gro...
<p>Immunohistochemical analysis of TLR2 expression level in rat renal tissues in different age group...