Age associations with plasma markers of MT and inflammation in HIVpos subjects.

<p>Plasma biomarkers were measured by ELISA in the plasma of subjects ranging from 24–81 years of age. (A) Individual associations between age iFABP, LPS, sCD14, sCD27, hsCRP, and IL-6. Pearson correlations were conducted on natural log transformed plasma concentrations. The solid line indicates the best fit regression line for parameters that were significantly correlated with age. P < 0.05 was considered a significant association. The Pearson r and exact p-value for each association is shown. (B) Heat map showing the plasma concentrations of all six markers in individual subjects ordered from youngest to oldest. The untransformed plasma concentrations were median centered and plotted. Grey = the median value, Red = below median, Blue = above median, black = missing value. The heat map was normalized to the range for each individual marker so that the fold change represented by each color is consistent across markers.