<p>Total kidney collagen content for each healthy mouse and each uninephrectomized mouse administered DOCA+NaCl is shown. In general, mice from the latter cohort exhibited higher kidney collagen content albeit there is a clear evidence of a distribution of collagen content in kidneys of mice within each cohort.</p
<p>(A) Gene expression of collagen type I (Coll I) in control and DN mice treated with saline or sul...
Background Interstitial fibrosis is associated with chronic renal failure. In addition to fibroblast...
<p>Some important fibrotic markers are highly expressed in the Gpr48 KO mice compared with the WT mi...
<p>(A) Lysates were extracted from mouse kidneys of the indicated groups, and subjected to immunoblo...
<p>Animals were euthanized on day 21 post infection (p.i.), perfused, and the kidneys were collected...
<p>Panel A: Renal collagen concentration (collagen content expressed as percentage of dry tissue wei...
<p>(A) Representative images of fibrillar collagen deposition shown by Sirius Red staining (in CD73<...
<p>Representative pictures of kidney sections from control (SHAM), uremic (NX) and liraglutide treat...
<p>(A) LDH (B) and γGT activities were measured in urine samples as markers of tubular injury (<i>n<...
<p>Data are means ± SEM for 12 mice per group; *p=0.0217. Pictures for macrophage staining display r...
The extent of scarring or renal interstitial collagen deposition in chronic kidney disease (CKD) can...
<p>(A) SDS-PAGE of collagen extracted from the skin (Coll S) and tail tendons (Coll T). Insert: West...
<p><b>Panels A-F: High power images of typical glomeruli stained with periodic acid-Schiff (PAS).</b...
<div><p>The extent of scarring or renal interstitial collagen deposition in chronic kidney disease (...
<p>(<b>A</b>) Representative macroscopic photographs of the kidneys. Scale bar = 5 mm. (<b>B</b>) Ki...
<p>(A) Gene expression of collagen type I (Coll I) in control and DN mice treated with saline or sul...
Background Interstitial fibrosis is associated with chronic renal failure. In addition to fibroblast...
<p>Some important fibrotic markers are highly expressed in the Gpr48 KO mice compared with the WT mi...
<p>(A) Lysates were extracted from mouse kidneys of the indicated groups, and subjected to immunoblo...
<p>Animals were euthanized on day 21 post infection (p.i.), perfused, and the kidneys were collected...
<p>Panel A: Renal collagen concentration (collagen content expressed as percentage of dry tissue wei...
<p>(A) Representative images of fibrillar collagen deposition shown by Sirius Red staining (in CD73<...
<p>Representative pictures of kidney sections from control (SHAM), uremic (NX) and liraglutide treat...
<p>(A) LDH (B) and γGT activities were measured in urine samples as markers of tubular injury (<i>n<...
<p>Data are means ± SEM for 12 mice per group; *p=0.0217. Pictures for macrophage staining display r...
The extent of scarring or renal interstitial collagen deposition in chronic kidney disease (CKD) can...
<p>(A) SDS-PAGE of collagen extracted from the skin (Coll S) and tail tendons (Coll T). Insert: West...
<p><b>Panels A-F: High power images of typical glomeruli stained with periodic acid-Schiff (PAS).</b...
<div><p>The extent of scarring or renal interstitial collagen deposition in chronic kidney disease (...
<p>(<b>A</b>) Representative macroscopic photographs of the kidneys. Scale bar = 5 mm. (<b>B</b>) Ki...
<p>(A) Gene expression of collagen type I (Coll I) in control and DN mice treated with saline or sul...
Background Interstitial fibrosis is associated with chronic renal failure. In addition to fibroblast...
<p>Some important fibrotic markers are highly expressed in the Gpr48 KO mice compared with the WT mi...